Kokutsov A
Akush Ginekol (Sofiia). 1991;30(3):59-64.
The author studied the hypotensive effect on women with hypertonic disease during climacteric and investigated their physical capacity for a period of one year. The object of the study was 56 women with climacteric syndrome during climacteric as 38 out of 56 women suffered from hypertonic disease (HD). A considerable reduction in the physical working capacity of women suffering from HD during climacteric 326 +/- 20 kgm/min was found. After the performed one-year treatment the physical working capacity was increased considerably to 606 +/- 23 kgm/min at p less than 0.001, to which an increase in the heart output (presented as heart frequency and arterial blood pressure) corresponded. The best manifested effect in recovery of the physical working capacity in patients with HD during climacteric was found after hypotensive therapy, but the combined (hypertensive and sedative) therapy was on the second place and the sedative therapy--on the third place.
作者研究了降压药对更年期高血压女性疾病的影响,并对她们的身体机能进行了为期一年的调查。研究对象为56名处于更年期的患有更年期综合征的女性,其中56名女性中有38名患有高血压疾病(HD)。研究发现,更年期患有HD的女性的体力工作能力显著下降,为326 +/- 20公斤米/分钟。经过为期一年的治疗后,体力工作能力显著提高到606 +/- 23公斤米/分钟,p值小于0.001,同时心输出量增加(表现为心率和动脉血压)。研究发现,在更年期患有HD的患者中,降压治疗后体力工作能力恢复的效果最为明显,但联合(降压和镇静)治疗位居第二,镇静治疗位居第三。