Kokutsov A, Petev L
Vutr Boles. 1990;29(6):57-62.
The effect of obsidan (propranolol) on the physical load tolerance was examined in 65 hypertensive patients up to 55 years of age treated for one year in outpatient conditions. The patients were classified into two groups: basic group of 45 patients with hypertension in initial II stage and a control group of 22 hypertensive patients. The basic group patients were treated in the course of one year with obsidan in doses of 80 up to 160 mg daily. The control group patients were treated irregularly with other hypotensive drugs. The dynamic indices were examined in rest and after physical load before and after treatment. The long-term treatment with obsidan led to an improvement of the general condition, effective lowering of the arterial pressure in rest and after physical load, increased tolerance to physical load, decreased double product.
在门诊条件下,对65名年龄在55岁以下、接受了一年治疗的高血压患者,研究了心得安(普萘洛尔)对身体负荷耐受性的影响。患者被分为两组:45名处于高血压初期II期的患者组成基础组,22名高血压患者组成对照组。基础组患者在一年的疗程中,每日服用80至160毫克的心得安。对照组患者不定期使用其他降压药治疗。在治疗前后,分别于静息状态和身体负荷后检测动态指标。长期使用心得安治疗可改善一般状况,有效降低静息和身体负荷后的动脉血压,提高身体负荷耐受性,降低双乘积。