Yehuda R, Bauer L O, Giller E L, Meyer R E
Psychiatry Department, University of Connecticut Health Center, Farmington.
Alcohol Clin Exp Res. 1991 Dec;15(6):1001-6. doi: 10.1111/j.1530-0277.1991.tb05201.x.
Eight male alcoholic inpatients in their 2nd week of treatment were presented with, and instructed to consume, a beverage described at one session as containing alcohol and at another as not containing alcohol. The beverage on each occasion did not, in fact, contain alcohol. The results indicated that when subjects believed they had consumed alcohol, the change in insulin from baseline was significantly greater at 10, 20, and 30 min following consumption. The findings suggest that the insulin response of alcoholics following ingestion of a carbohydrate-containing beverage is enhanced by the anticipation of ethanol.
八名处于治疗第二周的男性酒精成瘾住院患者被提供了一种饮料，并被要求饮用。在一次试验中，该饮料被描述为含有酒精，而在另一次试验中则被描述为不含酒精。事实上，每次提供的饮料都不含酒精。结果表明，当受试者认为自己饮用了酒精时，饮用后10分钟、20分钟和30分钟时，胰岛素相对于基线水平的变化显著更大。研究结果表明，酒精成瘾者在摄入含碳水化合物饮料后，对乙醇的预期会增强胰岛素反应。
