York J L
Research Institute on Addictions, Buffalo, New York 14203, USA.
J Stud Alcohol. 1995 May;56(3):328-36. doi: 10.15288/jsa.1995.56.328.
To document and compare the changes in alcohol intake over the drinking career in alcoholic (n = 273) and social (n = 152) drinkers and to relate the changes to age and to the prevalence of morning drinking.
Lifetime alcohol intake was assessed in face-to-face interviews by asking subjects to report drinking patterns during different "phases" of their drinking careers, beginning with the onset of regular drinking and continuing up to the present.
Alcohol consumption began at higher quantities and higher frequencies in alcoholics (prealcoholics) and rapidly escalated within a few years to values well out of the range of moderation. The alcohol intake of social drinkers at the beginning phase was only about 70% that of alcoholics. In contrast to alcoholics, the alcohol intake of social drinkers remained relatively constant across subsequent drinking phases at about three to four drinks per drinking occasion, with only a slight increase in the frequency of drinking over sequential drinking phases. The relationship of total alcohol consumption to age in alcoholics was described best by a curvilinear function, with alcohol consumption peaking near age 40.
Gender differences in consumption were decreased with adjustment for body water content. The higher initial alcohol intakes in alcoholics may reflect a lower sensitivity to the intoxicating effects of alcohol, or, alternatively, a greater ability of alcoholics to develop tolerance. The high prevalence of morning drinking in alcoholics compared to social drinkers reinforces the usefulness of morning drinking as a diagnostic tool, particularly for female alcoholism.
记录并比较酗酒者(n = 273)和社交饮酒者(n = 152)在饮酒生涯中酒精摄入量的变化,并将这些变化与年龄以及晨饮的患病率联系起来。
通过面对面访谈评估终生酒精摄入量,要求受试者报告其饮酒生涯中不同“阶段”的饮酒模式,从开始规律饮酒起直至目前。
酗酒者(戒酒前)开始饮酒时的量和频率更高,并且在几年内迅速攀升至远超适度范围的值。社交饮酒者在起始阶段的酒精摄入量仅约为酗酒者的70%。与酗酒者不同,社交饮酒者在随后的饮酒阶段中酒精摄入量相对保持恒定,每次饮酒场合约为三到四杯,只是在连续饮酒阶段饮酒频率略有增加。酗酒者中总酒精消费量与年龄的关系最好用曲线函数来描述,酒精消费量在40岁左右达到峰值。
通过调整身体含水量,饮酒量的性别差异减小。酗酒者较高的初始酒精摄入量可能反映出对酒精中毒作用的较低敏感性,或者,酗酒者具有更强的耐受能力。与社交饮酒者相比,酗酒者中晨饮的高患病率强化了晨饮作为一种诊断工具的实用性,特别是对于女性酗酒问题。