Barton Garry R, Sach Tracey H, Avery Anthony J, Jenkinson Claire, Doherty Michael, Whynes David K, Muir Kenneth R
School of Economics, University of Nottingham, Nottingham, UK.
Health Econ. 2008 Jul;17(7):815-32. doi: 10.1002/hec.1298.
We sought to compare the performance of the EQ-5D and SF-6D with regard to the criteria of practicality, convergent validity, and construct validity, the level of agreement between the two measures was also assessed. Responses from 1865 individuals aged >or= 45 years in one general practice were analysed. Of these, 93.1% completed the EQ-5D, compared with 86.4% for the SF-6D, where individuals who were older, female, of a lower occupational skill level, from an area of lower deprivation, or used prescribed medication were significantly less likely to complete the SF-6D. The performance of both measures was comparable with regard to both convergent and construct validities, as both the EQ-5D and SF-6D scores were closely related to scores on the EuroQol visual analogue scale (VAS) (p<0.001) and able to discriminate between people who did and did not take: (i) analgesics and (ii) other prescribed medication. Despite EQ-5D and SF-6D scores being highly correlated (p<0.001), individuals who were healthier (according to the VAS) had higher mean scores on the EQ-5D (p<0.001), whereas less healthy individuals had higher mean scores on the SF-6D (individuals with knee pain, osteoarthritis, back pain, rheumatoid arthritis, and hip pain had significantly lower mean scores on the EQ-5D, p<0.001).
我们试图比较EQ-5D和SF-6D在实用性、收敛效度和结构效度标准方面的表现，同时也评估了这两种测量方法之间的一致性水平。对一家普通诊所中1865名年龄≥45岁的个体的回答进行了分析。其中，93.1%的人完成了EQ-5D，而完成SF-6D的比例为86.4%，年龄较大、女性、职业技能水平较低、来自贫困程度较低地区或使用处方药的个体完成SF-6D的可能性显著较低。在收敛效度和结构效度方面，两种测量方法的表现相当，因为EQ-5D和SF-6D得分均与欧洲五维度健康量表视觉模拟量表（VAS）得分密切相关（p<0.001），并且能够区分服用和未服用以下药物的人群：（i）镇痛药和（ii）其他处方药。尽管EQ-5D和SF-6D得分高度相关（p<0.001），但（根据VAS）健康状况较好的个体在EQ-5D上的平均得分较高（p<0.001），而健康状况较差的个体在SF-6D上的平均得分较高（患有膝关节疼痛、骨关节炎、背痛、类风湿性关节炎和髋关节疼痛的个体在EQ-5D上的平均得分显著较低，p<0.001）。
