Nagel K, Adler L E, Bell J, Nagamoto H T, Freedman R
Department of Psychiatry, Denver Veterans Administration Medical Center, University of Colorado Health Sciences Center 80262.
Alcohol Clin Exp Res. 1991 Dec;15(6):978-81. doi: 10.1111/j.1530-0277.1991.tb05198.x.
The effects of lithium carbonate were assessed in a double-blind, placebo-controlled study of a small group of recently detoxified alcoholics. The patients were treated during their 2nd and 3rd week of abstinence. A previous study demonstrated the existence in these patients of a syndrome of mildly elevated psychomotor rate, including irritability, grandiosity, an increased need for social contact, loquaciousness, and sexual preoccupation. The intensity of this syndrome was significantly decreased by treatment with low dose lithium carbonate, with no effect of placebo treatment.
在一项针对一小群近期戒酒的酗酒者的双盲、安慰剂对照研究中，对碳酸锂的效果进行了评估。患者在戒酒的第二周和第三周接受治疗。先前的一项研究表明，这些患者存在一种精神运动速率轻度升高的综合征，包括易怒、夸大、社交接触需求增加、多话以及性关注。低剂量碳酸锂治疗可使该综合征的严重程度显著降低，而安慰剂治疗则无此效果。
