Ugol'nikov V A
Anesteziol Reanimatol. 1991 Nov-Dec(6):50-2.
Analgesia and hemodynamic parameters during epidural anesthesia with trimecaine (2% solution) in combination with fentanyl (200 micrograms) have been studied in 56 patients aged 28-84 years. During premedication 34 patients were, in addition to atropine, dimedrol and relanium, administered galanthamine (15 mg); 22 patients were not given galanthamine. Fentanyl was administered with the first doses of the anesthetic. It has been established that premedication with galanthamine reduced the time of anesthesia onset by 19.6% and decreased the initial anesthetic dose by 10.7%. The initial period of anesthesia was characterized by a 23% increase in the number of cases with retained baseline BP level, a 1.6-fold decrease in the value of BP lowering, a 2.4-fold slowing of the time of hypotonic reaction development and a 31% shortening of the time of bradycardia onset.
对56例年龄在28至84岁的患者，研究了三甲卡因（2%溶液）联合芬太尼（200微克）硬膜外麻醉期间的镇痛和血流动力学参数。在术前用药时，34例患者除了阿托品、苯海拉明和雷尼替丁外，还给予了加兰他敏（15毫克）；22例患者未给予加兰他敏。芬太尼与第一剂麻醉药同时给药。已确定，加兰他敏术前用药使麻醉起效时间缩短了19.6%，并使初始麻醉剂量降低了10.7%。麻醉初期的特点是，血压保持在基线水平的病例数增加了23%，血压下降值降低了1.6倍，低渗反应发生时间减慢了2.4倍，心动过缓发作时间缩短了31%。
