Vitenbek I A, Zolotareva A I, Kovalenko G A, Podol'skaia Ia V
Vestn Khir Im I I Grek. 1985 Dec;135(12):110-4.
Complex investigations of 2000 patients have shown that peridural anesthesia represents an adequate anesthesiologic defense of the patient from the operative stress. The potentiating effect of morphine is greater with greater doses and results in systemic elevation of sensory thresholds, suppression of the emotional component of perception of pain and a prolongation of anesthesia. A conclusion is made that in some patients operations on lower extremities and small pelvis organs should be performed under peridural anesthesia in combination with subnarcotic doses of sedative drugs.
对2000例患者进行的综合研究表明,硬膜外麻醉是对患者进行手术应激的一种充分的麻醉学防护措施。吗啡的增效作用随着剂量的增加而增强,会导致感觉阈值全身性升高、抑制疼痛感知的情感成分并延长麻醉时间。得出的结论是,对于一些患者,下肢和小骨盆器官的手术应在硬膜外麻醉联合亚麻醉剂量镇静药物的情况下进行。