Grossfeld R M
Zoology Department, North Carolina State University, Raleigh 27695-7617.
Ann N Y Acad Sci. 1991;633:318-30. doi: 10.1111/j.1749-6632.1991.tb15623.x.
The periaxonal and perineurial glia of crayfish and squid are strategically situated to regulate the neuronal microenvironment. Diverse molecules rapidly traverse the periaxonal sheath and a fraction of them enters the axons from glia or the glia from axons. The significance of these intercellular exchanges has not been tested directly. However, recent reports suggest that stress proteins, which probably are synthesized by both types of glia and transferred to axons, may be essential components by which the glia directly and indirectly assist neurons in tolerating ambient stress.
小龙虾和鱿鱼的轴突周围神经胶质细胞和神经束膜胶质细胞处于关键位置,可调节神经元的微环境。多种分子能迅速穿过轴突周围的鞘,其中一部分分子从神经胶质细胞进入轴突,或者从轴突进入神经胶质细胞。这些细胞间交换的重要性尚未得到直接验证。然而,最近的报告表明,应激蛋白可能由这两种神经胶质细胞合成并转移到轴突,它可能是神经胶质细胞直接或间接帮助神经元耐受环境压力的重要组成部分。