Martínez Vizcaíno V, Salcedo Aguilar F, Franquelo Gutiérrez R, Solera Martínez M, Sánchez López M, Serrano Martínez S, López García E, Rodríguez Artalejo F
Health and Social Research Centre, Universidad de Castilla-La Mancha, Cuenca, Spain.
Int J Obes (Lond). 2008 Jan;32(1):12-22. doi: 10.1038/sj.ijo.0803738. Epub 2007 Sep 25.
To assess the impact of a physical activity program on obesity in primary school children.
Cluster-randomized controlled trial with 10 intervention and 10 control schools.
A total of 1044 children, mean age 9.4 years (s.d.=0.7) at baseline, of the Province of Cuenca, Spain.
Recreational, non-competitive physical activity program conducted after school hours on school premises. The program consisted of three 90-min sessions per week, for 24 weeks.
Body mass index (BMI), triceps skin-fold thickness (TST) and percentage body fat. Secondary measures were blood lipids and blood pressure. Measurements were made at the beginning (September 2004) and at the end of the program (June 2005). Since schools rather than children were randomized, mixed regression models were used to adjust for individual-level covariates under cluster randomization.
There were no differences in BMI between the intervention and control groups. Compared with controls, intervention children showed a decrease in TST in both boys (-1.14 mm; 95% confidence interval (CI) -1.71 to -057; P<0.001) and girls (-1.55 mm; 95% CI -2.38 to -0.73; P<0.001), as well as a reduction in the percentage of body fat in girls (-0.58%; 95% CI -1.04 to -0.11; P=0.02). Furthermore, the intervention boys exhibited a decrease in apolipoprotein (apo) B levels (-4.59; 95% CI -8.81 to -0.37; P=0.03) and an increase in apo A-I levels (13.57; 95% CI 7.95-19.20; P<0.001). Blood lipid results in girls were very similar. No changes in total cholesterol, triglycerides or blood pressure were associated with the intervention in either sex, except for an increase in diastolic blood pressure (1.55 mm Hg; 95% CI 0.19-2.91; P=0.03) in the intervention versus control boys.
An after-school program of recreational physical activity reduced adiposity, increased apo A-I and decreased apo B in primary school children.
评估一项体育活动计划对小学生肥胖的影响。
整群随机对照试验,有10所干预学校和10所对照学校。
西班牙昆卡省共1044名儿童,基线时平均年龄9.4岁(标准差=0.7)。
在学校放学后在校园内开展的娱乐性、非竞争性体育活动计划。该计划每周有三次90分钟的课程,持续24周。
体重指数(BMI)、肱三头肌皮褶厚度(TST)和体脂百分比。次要指标为血脂和血压。在计划开始时(2004年9月)和结束时(2005年6月)进行测量。由于是对学校而非儿童进行随机分组,因此使用混合回归模型在整群随机化情况下对个体水平的协变量进行调整。
干预组和对照组的BMI没有差异。与对照组相比,干预组儿童的TST在男孩中有所下降(-1.14毫米;95%置信区间(CI)-1.71至-0.57;P<0.001),在女孩中也有所下降(-1.55毫米;95%CI-2.38至-0.73;P<0.001),女孩的体脂百分比也有所降低(-0.58%;95%CI-1.04至-0.11;P=0.02)。此外,干预组男孩的载脂蛋白(apo)B水平有所下降(-4.59;95%CI-8.81至-0.37;P=0.03),apo A-I水平有所升高(13.57;95%CI 7.95-19.20;P<0.001)。女孩的血脂结果非常相似。除了干预组男孩的舒张压升高(1.55毫米汞柱;95%CI 0.19-2.91;P=0.03)外,干预对两性的总胆固醇、甘油三酯或血压均无变化。
一项课后娱乐性体育活动计划可降低小学生的肥胖程度,提高apo A-I水平并降低apo B水平。