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精神病患者中氯丙嗪的不良反应。

Adverse reactions to chlorpromazine in psychiatric patients.

作者信息

Swett C

机构信息

Boston Collaborative Drug Surveillance Program, Boston University Medical Center, Waltham, Massachusetts 02154, USA.

出版信息

Dis Nerv Syst. 1974 Nov;35(11):509-11.

PMID:17896459
Abstract

In 470 consecutively monitored psychiatric inpatients who received chlorpromazine, adverse reactions attributed to the drug were reported in 150 (31.9%); and in three, the reaction was considered life-threatening (0.6%). Reactions were more frequent with higher daily doses and the intramuscular route was associated with earlier onset of a reaction.

摘要

在470名连续接受氯丙嗪监测的精神科住院患者中,有150名(31.9%)报告了归因于该药物的不良反应;其中有3例反应被认为危及生命(0.6%)。不良反应在每日剂量较高时更频繁出现,且肌肉注射途径与反应更早出现有关。

相似文献

1
Adverse reactions to chlorpromazine in psychiatric patients.精神病患者中氯丙嗪的不良反应。
Dis Nerv Syst. 1974 Nov;35(11):509-11.
2
A comparison of antipsychotic drug-defined daily doses versus chlorpromazine equivalent doses in patients with or without extrapyramidal motor symptoms.有或无锥体外系运动症状患者中抗精神病药物限定日剂量与氯丙嗪等效剂量的比较。
J Clin Psychopharmacol. 2010 Dec;30(6):741-3. doi: 10.1097/JCP.0b013e3181fab7ca.
3
Factors associated with antipsychotic dosing in psychiatric inpatients: a prospective study.精神科住院患者抗精神病药物剂量相关因素:一项前瞻性研究。
Int Clin Psychopharmacol. 2007 Jul;22(4):221-5. doi: 10.1097/YIC.0b013e3281084ea8.
4
Interpatient variations in antipsychotic therapy.抗精神病药物治疗中的患者间差异。
J Clin Psychiatry. 1985 May;46(5 Pt 2):3-5.
5
Psychopharmacological treatment of schizophrenia.
Schizophr Bull. 1975 Summer(13):27-45.
6
[Treatment with high doses of neuroleptics in the acute phase of mental diseases].[在精神疾病急性期使用高剂量抗精神病药物治疗]
Acta Psiquiatr Psicol Am Lat. 1979 Jun;25(2):157-60.
7
Replacement of chlorpromazine with other neuroleptics: effect on abnormal skin pigmentation and ocular changes.用其他抗精神病药物替代氯丙嗪:对皮肤色素沉着异常和眼部变化的影响。
J Psychiatry Neurosci. 1993 Jul;18(4):173-7.
8
Antipsychotic drug doses in a schizophrenia inpatient unit.
Aust N Z J Psychiatry. 1992 Dec;26(4):574-6. doi: 10.3109/00048679209072091.
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[Analysis of the consistency of the Forrest test with the dosage of chlorpromazine administered and the amount of the drug excreted daily in the urine (total fraction)].
Psychiatr Pol. 1970 Jul-Aug;4(4):429-34.
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Letter: Side effects of chlorpromazine and piperacetazine.信函:氯丙嗪和哌泊噻嗪的副作用。
Am J Psychiatry. 1974 Jun;131(6):722. doi: 10.1176/ajp.131.6.722.

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