Suppr超能文献

唾液中滥用药物分析及唾液药物浓度与血液浓度的相关性

[Analysis on the abused drugs in saliva and correlation of saliva drugs concentrations with blood concentrations].

作者信息

Li Peng-wang, Wang Yu-jin, Liu Jun-fang

机构信息

School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China.

出版信息

Fa Yi Xue Za Zhi. 2007 Aug;23(4):309-11, 315.

Abstract

Saliva is an easily collected body fluid and has simple composition. Some drugs concentrations in saliva can reflect their blood level. This paper analyzes the mechanisms of drug transfer from blood into saliva and the influencing factors, reviews the methods of sample collection, preparation, analysis of the abused drugs in saliva, and the relationship between abused drugs content in saliva and in blood. We believe that saliva is a valuable sample in clinic and forensic medicine. It is important in forensic science field to estimate abused drugs concentrations in blood by via their saliva concentrations.

摘要

唾液是一种易于采集的体液,成分简单。唾液中某些药物的浓度可以反映其血液水平。本文分析了药物从血液转移到唾液的机制及影响因素,综述了唾液中滥用药物的样本采集、制备、分析方法,以及唾液与血液中滥用药物含量的关系。我们认为唾液是临床和法医学中有价值的样本。通过唾液浓度估算血液中滥用药物的浓度在法医学领域很重要。

相似文献

2
Oral fluid collection: the neglected variable in oral fluid testing.口腔液采集:口腔液检测中被忽视的变量
Forensic Sci Int. 2005 Jun 10;150(2-3):165-73. doi: 10.1016/j.forsciint.2005.02.028.
3
Analytical techniques for drug detection in oral fluid.口腔液中药物检测的分析技术。
Ther Drug Monit. 2008 Apr;30(2):181-7. doi: 10.1097/FTD.0b013e3181685088.
4
Comment on "An evaluation of rapid point-of-collection oral fluid drug-testing devices".
J Anal Toxicol. 2004 Jan-Feb;28(1):75-6; author reply 76. doi: 10.1093/jat/28.1.75.
5
The sweat matrix: a new perspective for drugs analysis.
Skin Res Technol. 2015 Feb;21(1):129-30. doi: 10.1111/srt.12162. Epub 2014 Jul 25.
7
The recovery of illicit drugs from oral fluid sampling devices.从口腔液采样装置中回收非法药物。
Forensic Sci Int. 2007 Jan 5;165(1):78-84. doi: 10.1016/j.forsciint.2006.03.004. Epub 2006 Apr 18.
8
Testing for drugs of abuse in saliva and sweat.唾液和汗液中滥用药物的检测。
J Chromatogr B Biomed Sci Appl. 1998 Aug 21;713(1):111-35. doi: 10.1016/s0378-4347(97)00572-0.
10
Screening for drugs of abuse: which matrix, oral fluid or urine?药物滥用筛查:哪种基质,唾液还是尿液?
Ann Clin Biochem. 2011 Nov;48(Pt 6):531-41. doi: 10.1258/acb.2011.011116. Epub 2011 Sep 1.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验