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不同膳食谷物对实验大鼠血脂谱、肠道转运时间及主动脉组织病理学的影响。

The effect of varied dietary grains on plasma lipid profiles, gut transit time, and aorta histopathology in experimental rats.

作者信息

Kim Jung Yun, Kim Ju Hyeon, Lee Da Hee, Kim Sook He, Lee Sang Sun

机构信息

Department of Food and Nutrition, Hanyang University, Seoul 133-791, South Korea.

出版信息

Int J Vitam Nutr Res. 2007 Mar;77(2):99-106. doi: 10.1024/0300-9831.77.2.99.

DOI:10.1024/0300-9831.77.2.99
PMID:17896583
Abstract

This study was designed to investigate the influence of natural brown and black rice consumption on plasma lipid parameters, transit time, and thickness of the aortic wall in rats fed different combinations of grains. Fifty male rats were divided into five groups and raised for eight weeks with diets containing white rice (WR), white rice and brown rice (WRBR), white rice and black rice (WRBL), brown rice and black rice (BRBL), or wheat flour (WH). Gut transit time was the shortest in the BRBL group, and was longer in the order of WRBL, WRBR, WR, and WH group. Plasma lipid profiles differed significantly according to the grain combination. The BRBL group had the lowest levels of triglyceride (TG), total cholesterol (T-C), and low-density lipoprotein cholesterol (LDL-C), and the highest plasma high-density lipoprotein cholesterol (HDL-C) concentration among all groups. The aortic wall thickness hatro for body weight was lower in rats in order of BRBL, WRBR, WH, WRBL, and WR group. In conclusion, black rice and brown rice have anti-atherogenic effects by decreasing plasma lipide profiles and attenuating the thickness of the aortic wall.

摘要

本研究旨在调查食用天然糙米和黑米对喂食不同谷物组合的大鼠血浆脂质参数、转运时间和主动脉壁厚度的影响。将50只雄性大鼠分为五组,分别用含有白米(WR)、白米和糙米(WRBR)、白米和黑米(WRBL)、糙米和黑米(BRBL)或小麦粉(WH)的饮食饲养八周。BRBL组的肠道转运时间最短,其次是WRBL、WRBR、WR和WH组,转运时间依次延长。血浆脂质谱因谷物组合的不同而有显著差异。BRBL组的甘油三酯(TG)、总胆固醇(T-C)和低密度脂蛋白胆固醇(LDL-C)水平最低,在所有组中其血浆高密度脂蛋白胆固醇(HDL-C)浓度最高。按体重计算,大鼠主动脉壁厚度由低到高依次为BRBL、WRBR、WH、WRBL和WR组。总之,黑米和糙米通过降低血浆脂质水平和减轻主动脉壁厚度,具有抗动脉粥样硬化作用。

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