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无结构性心脏病时室性心动过速的管理

Management of ventricular tachycardia in the absence of structural heart disease.

作者信息

Morin Daniel P, Lerman Bruce B

机构信息

Division of Cardiology, Cornell University Medical Center, 525 East 68th Street, Starr-4, New York, NY 10021, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2007 Oct;9(5):356-63. doi: 10.1007/s11936-007-0055-9.

Abstract

Ventricular tachycardia most often arises from the ventricular outflow tracts in patients with apparently structurally normal hearts, and is often termed idiopathic ventricular tachycardia. These tachycardias are characterized by a left bundle branch block, inferior axis QRS morphology, and a unique electropharmacologic profile. The choice of treatment is dictated by the severity of symptoms, and ranges from observation for asymptomatic patients, to antiarrhythmic agents for those who are mildly to moderately symptomatic (eg, palpitations), to catheter-based ablation for those with more troubling symptoms or those who develop tachycardia-mediated cardiomyopathy. Antiarrhythmic therapy can be effective for arrhythmia suppression, and radiofrequency ablation has a high success rate (> 90%) with few procedural complications. In general, ventricular outflow tract tachycardia has a favorable prognosis. Exclusion of arrhythmogenic right ventricular dysplasia/cardiomyopathy is important due to significant disparities in prognosis and treatment.

摘要

在心脏结构明显正常的患者中,室性心动过速最常起源于心室流出道,通常被称为特发性室性心动过速。这些心动过速的特征是左束支传导阻滞、下轴QRS形态以及独特的电药理学特征。治疗方法的选择取决于症状的严重程度,范围从对无症状患者的观察,到对轻度至中度症状患者(如心悸)使用抗心律失常药物,再到对症状更严重或发展为心动过速介导的心肌病的患者进行导管消融。抗心律失常治疗对心律失常抑制可能有效,射频消融成功率高(>90%),手术并发症少。一般来说,心室流出道心动过速预后良好。由于预后和治疗存在显著差异,排除致心律失常性右心室发育不良/心肌病很重要。

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