Chugh Reema
Adult Congenital Heart Disease and Heart Disease in Pregnancy, Kaiser Foundation Hospitals, Department of Cardiology, 13652 Cantara Street, Area 308, Panorama City, CA 91402, USA.
Curr Treat Options Cardiovasc Med. 2007 Oct;9(5):414-27. doi: 10.1007/s11936-007-0062-x.
Medical advancements have made it possible for more women with congenital heart defects (CHDs) to carry successful pregnancies. Most CHD surgeries or interventions are palliative with persistent residua and sequelae exacerbated by the physiologic stresses of pregnancy. Preconception assessment, a tailored multidisciplinary approach during pregnancy, and a planned, elective delivery followed by careful postpartum monitoring may improve outcomes. Teratogenic medications should be stopped and changed to safer alternatives. Major hemodynamic changes in pregnancy, labor, and delivery may aggravate the underlying cardiovascular defects. Interventions or surgeries, when anticipated, should be performed before pregnancy. Antibiotic prophylaxis is indicated for nearly all palliated and unpalliated defects.
医学进步使更多患有先天性心脏病（CHD）的女性能够成功怀孕。大多数先天性心脏病手术或干预措施都是姑息性的，持续存在的残留病变和后遗症会因怀孕的生理压力而加重。孕前评估、孕期量身定制的多学科方法、计划好的择期分娩以及产后仔细监测可能会改善结局。致畸药物应停用并更换为更安全的替代品。怀孕、分娩和生产过程中的主要血流动力学变化可能会加重潜在的心血管缺陷。如有预期，干预措施或手术应在怀孕前进行。几乎所有姑息性和非姑息性缺陷都需要进行抗生素预防。
