Tipnis Neelesh A, Rudolph Colin D
Neelesh A. Tipnis, MD Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
Curr Treat Options Gastroenterol. 2007 Oct;10(5):391-400. doi: 10.1007/s11938-007-0039-6.
Gastroesophageal reflux (GER) is a common physiologic phenomenon in infants and children. GER that results in symptoms or complications--hence the evolution to GER disease (GERD)--warrants targeted evaluation and appropriate treatment. Judicious use of acid-suppression therapy remains the mainstay of pharmacologic treatment of GERD. However, recognition of treatment goals and potentials risks of acid suppression must be considered prior to initiation of therapy. The role of surgical intervention for GERD remains limited.
胃食管反流(GER)是婴幼儿和儿童常见的生理现象。导致症状或并发症的GER——即发展为胃食管反流病(GERD)——需要进行针对性评估和适当治疗。合理使用抑酸疗法仍然是GERD药物治疗的主要手段。然而,在开始治疗前必须考虑治疗目标和抑酸潜在风险。手术干预对GERD的作用仍然有限。