Esposito Ciro, Roberti Agnese, Turrà Francesco, Escolino Maria, Cerulo Mariapina, Settimi Alessandro, Farina Alessandra, Vecchio Pietro, Di Mezza Antonio
Department of Translational Medical Sciences, Pediatric Surgery, "Federico II" University of Naples, Naples, Italy.
Pediatric Health Med Ther. 2015 Jan 23;6:1-8. doi: 10.2147/PHMT.S46250. eCollection 2015.
Gastroesophageal reflux (GER), defined as the passage of gastric contents into the esophagus, is a physiologic process that occurs throughout the day in healthy infants and children. Gastroesophageal reflux disease (GERD) occurs when gastric contents flow back into the esophagus and produce symptoms. The most common esophageal symptoms are vomiting and regurgitation. Lifestyle changes are the first-line therapy in both GER and GERD; medications are explicitly indicated only for patients with GERD. Surgical therapies are reserved for children with intractable symptoms or who are at risk for life-threatening complications of GERD. The laparoscopic Nissen antireflux procedure is the gold standard for the treatment of this pathology. A literature search on PubMed and Cochrane Database was conducted with regard to the management of GERD in children to provide a view of state-of-the-art treatment of GERD in pediatrics.
胃食管反流（GER）定义为胃内容物进入食管，是一种生理过程，在健康婴幼儿和儿童中全天都会发生。当胃内容物反流回食管并产生症状时，就会发生胃食管反流病（GERD）。最常见的食管症状是呕吐和反流。生活方式改变是GER和GERD的一线治疗方法；仅对GERD患者明确推荐使用药物治疗。手术治疗适用于有难治性症状或有GERD危及生命并发症风险的儿童。腹腔镜Nissen抗反流手术是治疗这种病症的金标准。我们在PubMed和Cochrane数据库上进行了关于儿童GERD管理的文献检索，以呈现儿科GERD的最新治疗情况。
