Dietz Patricia M, Williams Selvi B, Callaghan William M, Bachman Donald J, Whitlock Evelyn P, Hornbrook Mark C
Division of Reproductive Health, Centers for Disease Control and Prevention, 4770 Buford Highway N.E., M.S. K-22, Atlanta, GA 30341, USA.
Am J Psychiatry. 2007 Oct;164(10):1515-20. doi: 10.1176/appi.ajp.2007.06111893.
This study estimated the prevalence of diagnosed depression and treatment among women before, during, and after pregnancies ending in live births.
A previously validated algorithm identified health plan members with at least one pregnancy between Jan. 1, 1998, and Dec. 31, 2001. Women with a pregnancy ending in one or more live births and continuously enrolled from 39 weeks before pregnancy through 39 weeks after pregnancy were eligible. Maternal depression was identified from the medical records. Depression treatment included antidepressant medication and/or mental health visits. The authors examined the prevalence of depression and treatments received.
Among 4,398 continuously enrolled women with eligible pregnancies ending in live births, 678 (15.4%) had depression identified during at least one pregnancy phase; 8.7%, 6.9%, and 10.4% had depression identified before, during, and/or after pregnancy, respectively. Among women with identified depression during the 39 weeks before pregnancy, 56.4% also had a depression diagnosis during pregnancy. Of women identified with depression during the 39 weeks following pregnancy, 54.2% had depression diagnoses either during or preceding pregnancy. Most women diagnosed with depression received antidepressant medications and/or had at least one mental health visit. Having at least one mental health visit did not vary before, during, or after pregnancy; however, antidepressant use was lower during pregnancy than before or after pregnancy.
Approximately one in seven women was identified with and treated for depression during 39 weeks before through 39 weeks after pregnancy, and more than half of these women had recurring indicators for depression.
本研究估计了在以活产告终的妊娠之前、期间和之后,女性中确诊抑郁症及接受治疗的患病率。
一种先前经验证的算法识别出了在1998年1月1日至2001年12月31日期间至少有一次妊娠的健康计划成员。妊娠以一次或多次活产告终且从妊娠前39周持续参保至妊娠后39周的女性符合条件。从医疗记录中识别出产妇抑郁症。抑郁症治疗包括抗抑郁药物治疗和/或心理健康就诊。作者研究了抑郁症的患病率及接受的治疗。
在4398名以活产告终且持续参保的符合条件的妊娠女性中,678名(15.4%)在至少一个妊娠阶段被确诊患有抑郁症;分别有8.7%、6.9%和10.4%在妊娠前、妊娠期间和/或妊娠后被确诊患有抑郁症。在妊娠前39周被确诊患有抑郁症的女性中,56.4%在妊娠期间也被诊断为抑郁症。在妊娠后39周被确诊患有抑郁症的女性中,54.2%在妊娠期间或妊娠前被诊断为抑郁症。大多数被诊断为抑郁症的女性接受了抗抑郁药物治疗和/或至少有一次心理健康就诊。妊娠前、妊娠期间和妊娠后进行至少一次心理健康就诊的情况没有差异;然而,妊娠期间抗抑郁药物的使用低于妊娠前或妊娠后。
在妊娠前39周至妊娠后39周期间,约七分之一的女性被确诊患有抑郁症并接受了治疗,其中超过一半的女性有抑郁症复发的迹象。