Malmsjö Malin, Ingemansson Richard, Sjögren Johan
Lund, Sweden From the Departments of Medicine and Cardiothoracic Surgery, Lund University Hospital.
Plast Reconstr Surg. 2007 Oct;120(5):1266-1275. doi: 10.1097/01.prs.0000279326.84535.2d.
: Vacuum-assisted closure has been adopted as the first-line treatment for poststernotomy mediastinitis as a result of the excellent clinical outcome achieved with its use. Scientific evidence regarding the mechanisms by which vacuum-assisted closure promotes wound healing has started to emerge, although knowledge regarding the effects on heart and lung function is still limited. The organs in the mediastinum are hemodynamically crucial, and in patients with poststernotomy mediastinitis, vulnerable bypass grafts and reduced cardiac function must be taken into consideration during vacuum-assisted closure therapy. This article provides an overview of the effects of vacuum-assisted closure on heart and lung function and summarizes the current knowledge on the mechanisms by which vacuum-assisted closure therapy promotes wound healing.
由于使用真空辅助闭合疗法取得了出色的临床效果，该疗法已被用作胸骨切开术后纵隔炎的一线治疗方法。尽管关于其对心脏和肺功能影响的知识仍然有限，但有关真空辅助闭合促进伤口愈合机制的科学证据已开始出现。纵隔内的器官在血流动力学方面至关重要，在胸骨切开术后纵隔炎患者中，进行真空辅助闭合治疗时必须考虑脆弱的旁路移植物和降低的心脏功能。本文概述了真空辅助闭合对心脏和肺功能的影响，并总结了目前关于真空辅助闭合疗法促进伤口愈合机制的知识。
