Ohshima Y, Beuth J, Ko H L, Roszkowski W, Pulverer G
St. Marianna University, Department of Microbiology, School of Medicine, Kawasaki, Japan.
Zentralbl Bakteriol. 1991 Dec;276(1):86-93. doi: 10.1016/s0934-8840(11)80222-7.
Lipoteichoic acid (LTA) was extracted from Staphylococcus saprophyticus strain S1 and tested for the capacity to induce hematopoietic and lymphatic cell proliferation. As compared to nontreated cells, the number of human bone marrow cells significantly increased in the presence of low LTA concentrations. Optimal growth was observed on the fifth day of in vitro incubation. After exposure to LTA, the lymphocyte proliferation rate also increased in a dose and time dependent manner. On the other hand, human epithelial cells and fibroblasts did not show enhanced growth activities in the presence of LTA.
从腐生葡萄球菌S1菌株中提取脂磷壁酸（LTA），并测试其诱导造血细胞和淋巴细胞增殖的能力。与未处理的细胞相比，在低LTA浓度存在的情况下，人骨髓细胞的数量显著增加。在体外培养的第五天观察到最佳生长情况。暴露于LTA后，淋巴细胞增殖率也呈剂量和时间依赖性增加。另一方面，在LTA存在的情况下，人上皮细胞和成纤维细胞未表现出增强的生长活性。
