Laswed T, Rizzo E, Guntern D, Doenz F, Denys A, Schnyder P, Qanadli S D
Department of Radiology, CHUV, University Hospital of Lausanne, Bugnon 46, 1012 Lausanne, Switzerland.
Eur Radiol. 2008 Feb;18(2):263-72. doi: 10.1007/s00330-007-0749-0. Epub 2007 Sep 26.
We evaluated 16-detector-row CT in the assessment of occlusive peripheral arterial disease (PAD) of the abdominal aorta and lower extremities using an adaptive method of acquisition to optimise arterial enhancement especially for the distal foot arteries. Thirty-four patients underwent transcatheter angiography (TCA) and CT angiography within 15 days. For each patient, table speed and rotation were selected according to the calculated optimal transit time of contrast material obtained after a single bolus test and two dynamic acquisitions at aorta and popliteal arteries. Analysis included image quality and detection of stenosis equal or greater than 50% on a patient basis and on an arterial segment basis. Sensitivity and specificity of CT were calculated with the TCA considered as the standard of reference. CT was conclusive in all segments with no technical failures even in difficult cases with occluded bypasses and aneurysms. On patient-basis analysis, the overall sensitivity and specificity to detect significant stenosis greater than 50% were both 100%. Segmental analysis shows high values of sensitivity and specificity ranging from 91 to 100% and from 81 to 100%, respectively, including distal pedal arteries. Sixteen-detector-row CT angiography using an adaptive acquisition improves the image quality and provides a reliable non-invasive technique to assess occlusive peripheral arterial disease, including distal foot arteries.
我们采用自适应采集方法评估了16排CT在腹主动脉和下肢闭塞性外周动脉疾病(PAD)评估中的应用,以优化动脉强化效果,特别是对于足部远端动脉。34例患者在15天内接受了经导管血管造影(TCA)和CT血管造影。对于每位患者,根据单次团注试验后获得的造影剂计算出的最佳通过时间以及在主动脉和腘动脉处进行的两次动态采集,选择床速和旋转速度。分析包括图像质量以及在患者层面和动脉节段层面检测等于或大于50%的狭窄。以TCA作为参考标准计算CT的敏感性和特异性。即使在存在闭塞性旁路和动脉瘤的困难病例中,CT在所有节段均得出结论,无技术故障。在患者层面分析中,检测大于50%的显著狭窄的总体敏感性和特异性均为100%。节段分析显示,敏感性和特异性的高值分别为91%至100%和81%至100%,包括足部远端动脉。使用自适应采集的16排CT血管造影可提高图像质量,并提供一种可靠的非侵入性技术来评估闭塞性外周动脉疾病,包括足部远端动脉。