Department of Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan.
Eur J Radiol. 2011 Aug;79(2):272-6. doi: 10.1016/j.ejrad.2010.05.009. Epub 2010 Jun 11.
The purpose of this study was to investigate correlations between the aorto-popliteal bolus transit speed and aortic and popliteal bolus transit time in order to evaluate the possibility for prediction of bolus transit speed by single test injection technique.
Approval was obtained from our institutional review board for this study, which included 42 patients, from all of whom written informed consent was obtained. Low-dose serial CT scanning after injection of 12 ml contrast material (300 mg/ml) at a rate of 3 ml/s followed by saline flush was performed twice, first at the level of the upper abdomen and second at the level of the knee joint. The times needed to reach peak enhancement of the upper abdominal aorta (T-aorta) and bilateral popliteal arteries (T-popliteal) were obtained, and aorto-popliteal bolus transit speeds between the abdominal aorta and popliteal arteries were calculated. ABI was recorded for the bilateral feet. The Pearson's product-moment correlation coefficient was used to investigate the correlation between the bolus transit speed and T-aorta, T-popliteal, ABI, and patient age.
The respective correlation coefficients for bolus transit speed on the one hand and T-aorta, T-popliteal, ABI, patient age on the other were -0.50, -0.84, 0.36, and -0.52.
The time to peak enhancement for popliteal arteries showed the strongest correlation with aorto-popliteal bolus transit speeds, and was considered to be the most accurate predictor for aorto-popliteal bolus transit speeds.
本研究旨在探讨股腘动脉内对比剂团注速度与主动脉及腘动脉对比剂团注时间之间的相关性,从而评估单次注射技术预测对比剂团注速度的可能性。
本研究获得了我院伦理委员会的批准,共纳入 42 例患者,所有患者均签署了知情同意书。采用 3ml/s 的速率经肘前静脉团注 12ml 浓度为 300mg/ml 的对比剂后,再以相同的速率注入生理盐水冲洗,分别对腹部上腔及膝关节水平行两次低剂量螺旋 CT 扫描。记录到达腹主动脉(T-aorta)及双侧腘动脉(T-popliteal)峰值增强时间,并计算腹主动脉与腘动脉之间的股腘动脉内对比剂团注速度。同时记录双侧踝肱指数(ABI)。采用 Pearson 积差相关系数分析对比剂团注速度与 T-aorta、T-popliteal、ABI 及患者年龄之间的相关性。
对比剂团注速度与 T-aorta、T-popliteal、ABI 及患者年龄的相关系数分别为-0.50、-0.84、0.36 和-0.52。
腘动脉的峰值增强时间与股腘动脉内对比剂团注速度相关性最强,被认为是预测股腘动脉内对比剂团注速度最准确的指标。