Romanik Małgorzata, Wojciechowska-Wieja Anna, Martirosian Gayane
Katedra i Zakład Mikrobiologii Lekarskiej Slaskiej Akademii Medycznej w Katowicach, Klinika Połoznictwa i Ginekologii Slaskiej Akademii Medycznej w Katowicach.
Ginekol Pol. 2007 Jun;78(6):488-91.
The diagnostic criteria and treatment of aerobic vaginitis--AV--have been summarized in this review. An expansion of mixed aerobic microflora, especially Group B Streptococcus--GBS, Escherichia coli--E. coli, Enterococcus spp., and the development of inflammation of the vaginal mucous membrane due to a decreasing amount of Lactobacillus spp., have been observed in women with AV. Disruptions of the vaginal ecosystem during AV cause an increase in pH to >6, a decrease in lactates concentration and an increase in proinflammatory cytokines concentration in vaginal discharge. An optimal treatment scheme for AV, which includes antibacterial agents and simultaneously normalizes the vaginal ecosystem, has not been established until today.
本文综述了需氧菌性阴道炎（AV）的诊断标准和治疗方法。在患有AV的女性中，已观察到需氧混合菌群的扩张，尤其是B族链球菌（GBS）、大肠杆菌（E. coli）、肠球菌属，以及由于乳酸杆菌属数量减少导致的阴道黏膜炎症。AV期间阴道生态系统的破坏导致pH值升高至>6，阴道分泌物中乳酸盐浓度降低，促炎细胞因子浓度升高。直到今天，尚未建立一种包括抗菌药物并同时使阴道生态系统正常化的AV最佳治疗方案。
