Gosbell A D, Barry W R, Favilla I, Burgess F
Department of Ophthalmology, Monash Medical Centre, Melbourne, Australia.
Aust N Z J Ophthalmol. 1991 Nov;19(4):327-33. doi: 10.1111/j.1442-9071.1991.tb00681.x.
The volume of intraocular tumours can be calculated from tumour height and cross-sectional areas measured in maximal orthogonal B-mode ultrasonograms, on the assumption that the tumour morphology is hemi-ellipsoidal. Comparison of this method with an accurate but more complex computer-aided B-mode ultrasonic tomographic method demonstrated a highly linear relationship with a correlation coefficient of 0.93. Furthermore, the comparison of cross-sectional areas measured from B-scan images and histological cross-sections in a small series of enucleated eyes demonstrated that tumour cross-sectional area measured from ultrasound images provides an accurate representation of the true physical size of the tumour in the globe. This method can be easily implemented with readily available B-mode ultrasound equipment. Unlike previously reported volume measurement methods, customised hardware or software is not required. The method is rapid and easy to perform, and may offer a useful standard method of measuring and monitoring intraocular tumours.
假设眼内肿瘤形态为半椭圆形，可根据在最大正交B型超声图中测量的肿瘤高度和横截面积来计算眼内肿瘤的体积。将该方法与一种准确但更复杂的计算机辅助B型超声断层扫描方法进行比较，结果显示二者具有高度线性关系，相关系数为0.93。此外，在一小系列摘除眼球的眼中，对B扫描图像测量的横截面积与组织学横截面积进行比较，结果表明，超声图像测量的肿瘤横截面积能准确反映眼球内肿瘤的实际物理大小。该方法可通过现成的B型超声设备轻松实现。与先前报道的体积测量方法不同，无需定制硬件或软件。该方法快速且易于实施，可能为测量和监测眼内肿瘤提供一种有用的标准方法。
