Verdecchia Arduino, De Angelis Roberta, Francisci Silvia, Grande Enrico
Reparto di Epidemiologia dei Tumori, Centro Nazionale di Epidemiologia, Sorveglianza e Promozione della Salute, Istituto Superiore di Sanità, Rome, Italy.
Tumori. 2007 Jul-Aug;93(4):337-44. doi: 10.1177/030089160709300403.
The Italian health care system is based on a regional responsibility and organization. Incidence, survival and prevalence of cancer patients were estimated for major cancer sites by single regions in Italy within a collaborative project "I TUMORI IN ITALIA" aimed at providing epidemiological information in a web site, www.tumori.net, for health operators, health programmers, epidemiologists and the general public. The aim of this paper is to present the methodology used to derive regional estimates of cancer burden indicators in Italy for major cancer sites.
Estimates require a complex methodology to be used. We present herein the methodology to provide regional estimates that involves a combined use of multiple methods to model and extrapolate patient survival to derive incidence and prevalence estimates and future projections.
Regional patient survival estimates in Italy are presented and discussed. Cancer survival has greatly improved over the years and differences between northern-central and southern regions have persisted. The fraction of patients cured from cancer is today over 50% for young men and women aged 15-44 and declines to 15%-25% at older ages (75-99).
We integrated different methods to derive estimates of cancer burden in Italy, at a regional level, in order to take advantage of all information available and to obtain the most reliable estimates. The value of producing regional estimates of cancer burden indicators was motivated by the lack of such information systematically on the Italian national territory.
意大利医疗保健系统基于地区责任和组织架构。在“意大利的肿瘤”这一合作项目中，由意大利各地区对主要癌症部位的癌症患者发病率、生存率和患病率进行了估算，该项目旨在通过网站www.tumori.net为医疗工作者、健康规划者、流行病学家及普通公众提供流行病学信息。本文旨在介绍用于得出意大利主要癌症部位癌症负担指标地区估算值的方法。
估算需要使用复杂的方法。我们在此介绍提供地区估算值的方法，该方法涉及综合运用多种方法来模拟和外推患者生存率，以得出发病率、患病率估算值及未来预测值。
展示并讨论了意大利各地区患者生存率估算值。多年来癌症生存率有了显著提高，北部 - 中部和南部地区之间的差异依然存在。如今，15 - 44岁的年轻男性和女性中癌症治愈患者的比例超过50%，而在老年（75 - 99岁）时这一比例降至15% - 25%。
我们整合了不同方法来得出意大利地区层面的癌症负担估算值，以便利用所有可用信息并获得最可靠的估算值。生成癌症负担指标地区估算值的意义在于意大利全国范围内缺乏此类系统信息。
