皮埃蒙特和瓦莱达奥斯塔癌症负担估计数。

Estimates of cancer burden in Piedmont and Aosta Valley.

作者信息

Rosso Stefano, Sacchetto Lidia, Giacomin Adriano, Foschi Roberto, De Angelis Roberta, Rossi Silvia, Zanetti Roberto

出版信息

Tumori. 2013 May-Jun;99(3):269-76. doi: 10.1177/030089161309900301.

DOI:10.1177/030089161309900301

PMID:24158055

Abstract

AIMS AND BACKGROUND

Cancer registration in Piedmont currently covers the city of Turin and the province of Biella, together representing 24% of the regional population. The objective of this paper is to provide estimates of the incidence and mortality rates and prevalence proportions for cancer of the lung, breast, cervix, prostate, colon-rectum and stomach and melanoma of the skin for 2012 and the time trends up to 2015 for the Piedmont and Aosta Valley regions.

METHODS

The estimates were obtained by applying the MIAMOD method, a statistical back-calculation approach to derive incidence and prevalence figures starting from mortality and relative survival data. Published data from the Italian cancer registries were modeled in order to estimate the regional cancer survival. The MIAMOD estimates were also compared with those obtained by applying a method based on the mortality-incidence and prevalence-incidence ratios.

RESULTS

The most frequently diagnosed cancers in absolute terms were prostate, colorectal, breast and lung cancer with about 5,000, 4,700, 3,300, and 2,900 new cases, respectively, in 2012. Incidence rates were rising for melanoma in both sexes and lung cancer in women, while they diminished for cervical and stomach cancer. For prostate cancer and male lung cancer the rates initially increased but were estimated to decrease in the most recent period. Colorectal cancer also increased up to the 1990s but was estimated to reach a plateau in the final years of estimation. Prevalence increased for all the considered cancers with the exception of cervical cancer. Mortality was declining for all considered cancers with the exception of lung cancer in women.

CONCLUSIONS

Monitoring indicators of the cancer burden is crucial for setting priorities among possible health system activities in a limited-resource setting. Piedmont has long invested in organized, population-based screening programs: these will have to be extended and accompanied by greater efforts in primary prevention.

摘要

目的与背景

皮埃蒙特地区目前的癌症登记覆盖都灵市和比耶拉省，这两个地区的人口占该地区总人口的24%。本文的目的是提供2012年皮埃蒙特和奥斯塔山谷地区肺癌、乳腺癌、宫颈癌、前列腺癌、结肠直肠癌、胃癌以及皮肤黑色素瘤的发病率、死亡率和患病率估计值，以及截至2015年的时间趋势。

方法

通过应用MIAMOD方法获得估计值，MIAMOD是一种统计反向计算方法，可从死亡率和相对生存数据推导出发病率和患病率数据。对意大利癌症登记处公布的数据进行建模，以估计地区癌症生存率。还将MIAMOD估计值与应用基于死亡率-发病率和患病率-发病率比的方法获得的估计值进行了比较。

结果

按绝对病例数计算，最常诊断出的癌症是前列腺癌、结肠直肠癌、乳腺癌和肺癌，2012年新发病例分别约为5000例、4700例、3300例和2900例。黑色素瘤在男女中的发病率均呈上升趋势，女性肺癌发病率也在上升，而宫颈癌和胃癌发病率则下降。前列腺癌和男性肺癌发病率最初上升，但估计在最近一段时间有所下降。结肠直肠癌在20世纪90年代之前也有所上升，但估计在估计期的最后几年达到平稳状态。除宫颈癌外，所有考虑的癌症患病率均有所上升。除女性肺癌外，所有考虑的癌症死亡率均在下降。