Kindo A J, Shams N R, Srinivasan V, Kalyani J, Mallika M
Department of Microbiology, Sri Ramachandra Medical College and Research Institute, Chennai - 600 116, India.
Indian J Med Microbiol. 2007 Jul;25(3):291-3. doi: 10.4103/0255-0857.34780.
A case of zygomycosis presenting with non-healing multiple discharging sinuses in a diabetic patient is reported here. The debrided tissue on histopathological examination revealed dense infiltration with aseptate fungal hyphae. Potassium hydroxide mount showed hyaline aseptate hyphae suggestive of zygomycosis. On culture, Absidia corymbifera was isolated. The patient responded to surgical debridement and therapy with amphotericin B followed by itraconazole.
本文报道了一例糖尿病患者出现多发性不愈合排脓窦道的接合菌病病例。组织病理学检查显示清创组织中有大量无隔真菌菌丝浸润。氢氧化钾涂片显示透明无隔菌丝,提示接合菌病。培养分离出伞枝犁头霉。患者对手术清创及两性霉素B治疗后改用伊曲康唑治疗有反应。