Wadhera Raman, Vashist Aarushi
Pt. B.D Sharma PGIMS Rohtak, 3/7J Medical Campus, Rohtak, Haryana India.
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):3367-3369. doi: 10.1007/s12070-020-02001-w. Epub 2020 Jul 25.
Nasal mucormycosis is a rare opportunistic infection of the nasal cavity and paranasal sinuses caused by saprophytic fungi which can rapidly lead to death. It usually affects individuals with poorly controlled diabetes mellitus (especially those with ketoacidosis), solid malignancies, iron overload, extensive burns, in patients undergoing treatment with glucocorticosteroid agents and in patients with neutropenia related to haematologic malignancies. Presentation of nasal mucormycosis is always very extensive, but in some patients, it can present in chronic indolent form also. Here, we present a case of 65-year old male with a history of exposed nasal bone after nasal trauma 8 months back. His diabetes was in control with oral hypoglycaemics. Debridement and local flap closure was done. Culture showed the growth of and in HPE, the fungus was seen branching at right angles. So, we conclude that the possibility of nasal mucormycosis should always be borne in mind so that early and effective treatment can be initiated on time to decrease the morbidity and mortality.
鼻毛霉菌病是一种由腐生真菌引起的鼻腔和鼻窦罕见的机会性感染,可迅速导致死亡。它通常影响糖尿病控制不佳的个体(尤其是那些患有酮症酸中毒的患者)、实体恶性肿瘤患者、铁过载患者、大面积烧伤患者、接受糖皮质激素治疗的患者以及与血液系统恶性肿瘤相关的中性粒细胞减少患者。鼻毛霉菌病的表现总是非常广泛,但在一些患者中,它也可以以慢性惰性形式出现。在此,我们报告一例65岁男性患者,8个月前鼻外伤后鼻骨外露。他的糖尿病通过口服降糖药得到控制。进行了清创和局部皮瓣闭合。培养显示有生长,在苏木精-伊红染色切片中,可见真菌呈直角分支。因此,我们得出结论,应始终牢记鼻毛霉菌病的可能性,以便及时启动早期有效治疗,降低发病率和死亡率。