Mitchell P F, Andrews S, Fox A M, Catts S V, Ward P B, McConaghy N
School of Psychology, University of New South Wales, Australia.
Biol Psychol. 1991 Oct-Dec;32(2-3):101-24. doi: 10.1016/0301-0511(91)90004-z.
Attentional dysfunctions in schizophrenia were investigated using a sentence priming task. Schizophrenic patients and healthy control subjects were presented with sentences to which they were required to make a response based on either semantic or physical stimulus features. Schizophrenics' behavioural responses were slower than those of controls, particularly when attending to semantic relationships, but their performance was no less accurate. Both the P300 and the N400 components of the event-related potentials (ERPs) recorded to the sentence completions were attenuated in the schizophrenic sample. The results are interpreted in terms of a deficit in the active maintenance of semantic information in memory and the integration of new information with this representation.
使用句子启动任务对精神分裂症患者的注意力功能障碍进行了研究。向精神分裂症患者和健康对照受试者呈现句子，要求他们根据语义或物理刺激特征做出反应。精神分裂症患者的行为反应比对照组慢，尤其是在关注语义关系时，但他们的表现同样准确。在句子完成任务中记录的事件相关电位（ERP）的P300和N400成分在精神分裂症样本中均减弱。研究结果被解释为记忆中语义信息的主动维持以及新信息与该表征整合方面的缺陷。
