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解释不同种族人群出生体重的差异。Generation R研究。

Explaining differences in birthweight between ethnic populations. The Generation R Study.

作者信息

Troe E J W M, Raat H, Jaddoe V W V, Hofman A, Looman C W N, Moll H A, Steegers E A P, Verhulst F C, Witteman J C M, Mackenbach J P

机构信息

The Generation R Study Group, Erasmus Medical Centre, Rotterdam, The Netherlands.

出版信息

BJOG. 2007 Dec;114(12):1557-65. doi: 10.1111/j.1471-0528.2007.01508.x. Epub 2007 Sep 27.

Abstract

OBJECTIVE

To examine whether differences in birthweight of various ethnic groups residing in The Netherlands can be explained by determinants of birthweight.

DESIGN

Population-based birth cohort study.

SETTING

Data of pregnant women and their partners in Rotterdam, The Netherlands.

POPULATION

We examined data of 6044 pregnant women with a Dutch, Moroccan, Turkish, Capeverdean, Antillean, Surinamese-Creole, Surinamese-Hindustani and Surinamese-other ethnic background.

METHODS

Regression analyses were used to assess the impact of biomedical, socio-demographic and lifestyle-related determinants on birthweight differences.

MAIN OUTCOME MEASURE

Birthweight was established immediately after delivery in grams.

RESULTS

Compared with mean birthweight of offspring of Dutch women (3485 g, SD 555), the mean birthweight was lower in all non-Dutch populations, except in Moroccans. Differences ranged from an 88-g lower birthweight in offspring of the Turkish women to a 424-g lower birthweight in offspring of Surinamese-Hindustani women. Differences in gestational age, maternal and paternal height largely explained the lower birthweight in the Turkish, Antillean, Surinamese-Creole and Surinamese-other populations. Differences in birthweight between the Dutch and the Capeverdean and Surinamese-Hindustani populations could only partly be explained by the studied determinants.

CONCLUSIONS

These results confirm significant differences in birthweight between ethnic populations that can only partly be understood from established determinants of birthweight. The part that is understood points to the importance of determinants that cannot easily be modified, such as parental height. Further study is necessary to obtain a fuller understanding.

摘要

目的

探讨居住在荷兰的不同种族群体出生体重差异是否可由出生体重的决定因素来解释。

设计

基于人群的出生队列研究。

地点

荷兰鹿特丹孕妇及其伴侣的数据。

研究对象

我们研究了6044名具有荷兰、摩洛哥、土耳其、佛得角、安的列斯、苏里南克里奥尔、苏里南印度斯坦和苏里南其他种族背景的孕妇的数据。

方法

采用回归分析来评估生物医学、社会人口学和生活方式相关决定因素对出生体重差异的影响。

主要观察指标

出生后立即以克为单位确定出生体重。

结果

与荷兰女性后代的平均出生体重(3485克,标准差555)相比,除摩洛哥人外,所有非荷兰人群的平均出生体重均较低。差异范围从土耳其女性后代出生体重低88克到苏里南印度斯坦女性后代出生体重低424克。孕周、母亲和父亲身高的差异在很大程度上解释了土耳其、安的列斯、苏里南克里奥尔和苏里南其他人群出生体重较低的原因。荷兰人与佛得角和苏里南印度斯坦人群之间的出生体重差异只能部分地由所研究的决定因素来解释。

结论

这些结果证实了不同种族群体之间出生体重存在显著差异,而这些差异只能部分地从已确定的出生体重决定因素中得到理解。已理解的部分表明了诸如父母身高这类不易改变的决定因素的重要性。有必要进行进一步研究以获得更全面的理解。

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