哪些耳鸣患者能从经颅磁刺激中获益？

Which tinnitus patients benefit from transcranial magnetic stimulation?

作者信息

Kleinjung Tobias, Steffens Thomas, Sand Philipp, Murthum Tobias, Hajak Goeran, Strutz Juergen, Langguth Berthold, Eichhammer Peter

机构信息

Department of Otorhinolaryngology, University of Regensburg, Germany.

出版信息

Otolaryngol Head Neck Surg. 2007 Oct;137(4):589-95. doi: 10.1016/j.otohns.2006.12.007.

DOI:10.1016/j.otohns.2006.12.007

PMID:17903575

Abstract

OBJECTIVES

Chronic tinnitus is associated with hyperactivity of the central auditory system. Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the temporal cortex has been proposed as a treatment for chronic tinnitus. This study determined the factors that predict a beneficial outcome with rTMS treatment.

STUDY DESIGN

Forty-five patients with chronic tinnitus underwent 10 sessions of low-frequency rTMS to their left auditory cortex. The treatment outcome was assessed with a tinnitus questionnaire. Therapeutic success was related to the patients' clinical characteristics.

RESULTS

A significant reduction in tinnitus complaints occurred after rTMS. In the questionnaire, 40% of the patients improved by five points or more. Treatment responders were characterized by shorter duration of tinnitus complaints and no hearing impairment.

CONCLUSION

Tinnitus-related neuroplastic changes might be less pronounced in patients with normal hearing and a short history of complaints. This could explain why those patients benefitted more from rTMS treatment.

摘要