文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

经颅磁刺激治疗耳鸣:一种新的线圈定位方法及初步结果。

Transcranial magnetic stimulation for the treatment of tinnitus: a new coil positioning method and first results.

作者信息

Langguth Berthold, Zowe Marc, Landgrebe Michael, Sand Philipp, Kleinjung Tobias, Binder Harald, Hajak Göran, Eichhammer Peter

机构信息

Department of Psychiatry, Psychotherapy and Psychosomatics, University of Regensburg, Universitätsstrasse 84, 93053 Regensburg, Germany.

出版信息

Brain Topogr. 2006 Summer;18(4):241-7. doi: 10.1007/s10548-006-0002-1. Epub 2006 Jul 15.


DOI:10.1007/s10548-006-0002-1
PMID:16845596
Abstract

Auditory phantom perceptions are associated with hyperactivity of the central auditory system. Neuronavigation guided repetitive transcranial magnetic stimulation (rTMS) of the area of increased activity was demonstrated to reduce tinnitus perception. The study aimed at developing an easy applicable standard procedure for transcranial magnetic stimulation of the primary auditory cortex and to investigate this coil positioning strategy for the treatment of chronic tinnitus in clinical practice. The left gyrus of Heschl was targeted in 25 healthy subjects using a frameless stereotactical system. Based on individual scalp coordinates of the coil, a positioning strategy with reference to the 10--20-EEG system was developed. Using this coil positioning approach we started an open treatment trial. 28 patients with chronic tinnitus received 10 sessions of rTMS (intensity 110% of motor threshold, 1 Hz, 2000 Stimuli/day). Being within a range of about 20 mm diameter, the scalp coordinates for stimulating the primary auditory cortex allowed to determine a standard procedure for coil positioning. Clinical validation of this coil positioning method resulted in a significant improvement of tinnitus complaints (p<0.001). The newly developed coil positioning strategy may have the potential to offer a more easy-to-use stimulation approach for treating chronic tinnitus as compared with highly sophisticated, imaging guided treatment methods.

摘要

听觉幻听与中枢听觉系统的过度活跃有关。经证实,在神经导航引导下对活动增强区域进行重复经颅磁刺激(rTMS)可减轻耳鸣感知。该研究旨在开发一种易于应用的标准程序用于对初级听觉皮层进行经颅磁刺激,并在临床实践中研究这种线圈定位策略用于治疗慢性耳鸣。使用无框架立体定向系统对25名健康受试者的左侧颞横回进行定位。基于线圈的个体头皮坐标,制定了一种参照10 - 20脑电图系统的定位策略。采用这种线圈定位方法,我们启动了一项开放性治疗试验。28例慢性耳鸣患者接受了10次rTMS治疗(强度为运动阈值的110%,1Hz,每天2000次刺激)。刺激初级听觉皮层的头皮坐标在直径约20毫米的范围内,这使得能够确定一种线圈定位的标准程序。这种线圈定位方法的临床验证结果显示耳鸣症状有显著改善(p<0.001)。与高度复杂的成像引导治疗方法相比,新开发的线圈定位策略可能有潜力提供一种更易于使用的刺激方法来治疗慢性耳鸣。

相似文献

[1]
Transcranial magnetic stimulation for the treatment of tinnitus: a new coil positioning method and first results.

Brain Topogr. 2006

[2]
Long-term effects of repetitive transcranial magnetic stimulation (rTMS) in patients with chronic tinnitus.

Otolaryngol Head Neck Surg. 2005-4

[3]
[Low frequency repetitive transcranial magnetic stimulation (rTMS) for the treatment of chronic tinnitus--are there long-term effects?].

Psychiatr Prax. 2004-11

[4]
rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning.

Neurophysiol Clin. 2009-4-1

[5]
Comparison of "standard" and "navigated" procedures of TMS coil positioning over motor, premotor and prefrontal targets in patients with chronic pain and depression.

Neurophysiol Clin. 2010-1-22

[6]
Short-term effects of single repetitive TMS sessions on auditory evoked activity in patients with chronic tinnitus.

J Neurophysiol. 2010-6-30

[7]
Efficacy of repetitive transcranial magnetic stimulation for the treatment of refractory chronic tinnitus: a randomized, placebo controlled study.

Neuro Endocrinol Lett. 2010

[8]
The impact of auditory cortex activity on characterizing and treating patients with chronic tinnitus--first results from a PET study.

Acta Otolaryngol Suppl. 2006-12

[9]
Which tinnitus patients benefit from transcranial magnetic stimulation?

Otolaryngol Head Neck Surg. 2007-10

[10]
Effect of 1 Hz repetitive transcranial magnetic stimulation over the auditory cortex on audiometry and otoacustic emissions.

Brain Topogr. 2012-1-19

引用本文的文献

[1]
Perceptual and Cognitive Effects of Focal Transcranial Direct Current Stimulation of Auditory Cortex in Tinnitus.

Neuromodulation. 2025-1

[2]
Focal tDCS of auditory cortex in chronic tinnitus: A randomized controlled mechanistic trial.

Clin Neurophysiol. 2024-2

[3]
Unresolved Issues Associated with Transcranial Magnetic Stimulation (TMS) Treatment of Chronic Tinnitus.

J Clin Med. 2023-7-12

[4]
The neuroanatomical hallmarks of chronic tinnitus in comorbidity with pure-tone hearing loss.

Brain Struct Funct. 2023-7

[5]
Sequential Prefrontal and Temporoparietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment of Tinnitus With and Without Comorbid Depression: A Case Series and Systematic Review.

Front Neurol. 2022-5-19

[6]
Comparison of hemodynamic changes after repetitive transcranial magnetic stimulation over the anatomical hand knob and hand motor hotspot: A functional near-infrared spectroscopy study.

Restor Neurol Neurosci. 2020

[7]
Single-Session of Combined tDCS-TMS May Increase Therapeutic Effects in Subjects With Tinnitus.

Front Neurol. 2020-3-27

[8]
RTMS parameters in tinnitus trials: a systematic review.

Sci Rep. 2019-8-21

[9]
Neuronavigated Versus Non-navigated Repetitive Transcranial Magnetic Stimulation for Chronic Tinnitus: A Randomized Study.

Trends Hear. 2019

[10]
Effects of Acoustic Paired Associative Stimulation on Late Auditory Evoked Potentials.

Brain Topogr. 2019-5

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索