Stotland Naomi E, Washington A Eugene, Caughey Aaron B
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, School of Medicine, San Francisco, CA, USA.
Am J Obstet Gynecol. 2007 Oct;197(4):378.e1-5. doi: 10.1016/j.ajog.2007.05.048.
The purpose of this study was to examine the relationship between prepregnancy body mass index (BMI) and length of gestation at term.
This was a retrospective study of 9336 births at the University of California, San Francisco, at > or = 37 weeks' gestation. We performed univariate and multivariable analyses of the associations between prepregnancy BMI and length of gestation (> or = 40, > or = 41, and > or = 42 weeks' gestation).
Overweight women were more likely to deliver at > or = 40, > or = 41, and > or = 42 weeks' gestation than were women who were underweight or normal weight. In multivariable analyses, higher prepregnancy BMI was associated with higher risk of progressing past 40 weeks. Obese women had 69% higher adjusted odds of reaching 42 weeks' gestation, compared with women of normal prepregnancy BMI (adjusted odds ratio, 1.69; 95% confidence interval, 1.23-2.31).
Higher BMI is associated with prolonged gestation at term. Achieving optimal BMI before conception may reduce the risk of postterm pregnancy and its associated complications.
本研究旨在探讨孕前体重指数(BMI)与足月妊娠时长之间的关系。
这是一项对加利福尼亚大学旧金山分校9336例妊娠≥37周分娩病例的回顾性研究。我们对孕前BMI与妊娠时长(≥40周、≥41周和≥42周妊娠)之间的关联进行了单变量和多变量分析。
超重女性相比于体重过轻或体重正常的女性,更有可能在妊娠≥40周、≥41周和≥42周时分娩。在多变量分析中,孕前BMI越高,超过40周妊娠进展的风险越高。与孕前BMI正常的女性相比,肥胖女性达到42周妊娠的校正比值比高69%(校正比值比为1.69;95%置信区间为1.23 - 2.31)。
较高的BMI与足月妊娠延长有关。在受孕前达到最佳BMI可能会降低过期妊娠及其相关并发症的风险。