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中国过期产儿的流行情况及其相关的产妇危险因素:来自 2012 年至 2016 年期间 600 多万例在医疗机构出生的婴儿数据。

Prevalence of postterm births and associated maternal risk factors in China: data from over 6 million births at health facilities between 2012 and 2016.

机构信息

National Office for Maternal and Child Health Surveillance of China, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, Sichuan, China.

出版信息

Sci Rep. 2019 Jan 22;9(1):273. doi: 10.1038/s41598-018-36290-7.

DOI:10.1038/s41598-018-36290-7
PMID:30670707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6342977/
Abstract

Postterm births are associated with an increased risk of adverse perinatal outcomes, but few studies have investigated the epidemiological characteristics of postterm births. We aimed to estimate the prevalence of postterm births and examine the potential association between maternal sociodemographic and obstetric characteristics and postterm births. Data were collected from China's National Maternal Near Miss Surveillance System, 2012-2016. A logistic regression was used to assess the association between sociodemographic and obstetric characteristics and postterm births. A Poisson regression was used to determine the crude and adjusted trends of postterm births over time across regions. Among the 6,240,830 singleton births with gestational periods of 37 weeks or longer, 1.16% were postterm. The prevalence of postterm births was significantly higher in the western region and among mothers who delivered at a level ≤2 hospital, had a lower education, or were younger. A reduced risk of postterm births was observed among primiparous women, mothers who previously had a caesarean section, mothers with pregnancy complications, and mothers with ten or more antenatal visits. The risk of postterm births decreased as the number of antenatal visits increased. The overall postterm birth rates significantly decreased from 1.49% in 2012 to 0.70% in 2016. The postterm birth rates were markedly reduced in the east, central, and west regions, and the rate of the decrease was greater in the east than in the west. Furthermore, substantial decreases were observed across regions in 2014 and 2016. In conclusion, multiple sociodemographic and obstetric factors are associated with the prevalence of postterm births. A significant decreasing trend in postterm birth rates was observed in China.

摘要

过期产与围产儿不良结局风险增加相关,但很少有研究调查过期产的流行病学特征。本研究旨在评估过期产的发生率,并探讨产妇社会人口学和产科特征与过期产的潜在关联。数据来自中国国家孕产妇严重不良结局监测系统,时间为 2012-2016 年。采用 logistic 回归评估社会人口学和产科特征与过期产的关系。采用 Poisson 回归分析不同地区过期产随时间的粗趋势和调整趋势。在 6240830 例孕周≥37 周的单胎分娩中,过期产占 1.16%。西部地区和在级别≤2 医院分娩、文化程度较低、年龄较小的产妇过期产发生率显著较高。初产妇、有剖宫产史、有妊娠并发症、产检≥10 次的产妇过期产风险较低。产检次数增加,过期产风险降低。总的过期产率从 2012 年的 1.49%显著下降到 2016 年的 0.70%。东部、中部和西部地区过期产率明显下降,东部地区下降幅度大于西部地区。此外,2014 年和 2016 年各地区过期产率均显著下降。总之,多种社会人口学和产科因素与过期产的发生率有关。中国过期产率呈显著下降趋势。

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