Sotoudehmanesh Rasoul, Hedayat Anooshirvan, Shirazian Nahid, Shahraeeni Shadi, Ainechi Sanaz, Zeinali Fatemeh, Kolahdoozan Shadi
Digestive Disease Research Center, Medical Sciences/University of Tehran, Shariati Hospital, North Kargar Ave, Tehran, Iran.
Endocrine. 2007 Jun;31(3):238-41. doi: 10.1007/s12020-007-0045-4.
Endoscopic ultrasonography has been accepted as a sensitive modality for preoperative tumor localization in pancreas. We have aimed to determine the performance characteristics of endoscopic ultrasonography in pancreatic insulinoma localization and evaluation of relationship between the tumor size and serum-c peptide level, lowest glucose level and insulin level.
Patients suspicious to insulinoma according to clinical and laboratory findings were included. Endoscopic ultrasonography was performed and if a tumor was identified, the patient was referred for surgery.
A total of 52 patients (24 male and 28 female) with mean age of 42.4 years underwent EUS and 43 patients underwent surgery. In one patient, a tumor was identified both by transabdominal ultrasonography and abdominal CT scan. The overall sensitivity and accuracy of endoscopic ultrasonography for detection of insulinoma was 89.5% and 83.7% respectively. The sensitivity of endoscopic ultrasonography for detection of lesions in pancreatic head, body and tail was 92.6%, 78.9%, and 40.0%, respectively. There was no relationship between c-peptide, lowest blood glucose, insulin blood levels and tumor size in surgery.
EUS is an accurate method for detection of insulinoma. The accuracy depends on the location of the tumor and is greatest for tumors in the pancreatic head.
内镜超声已被公认为是胰腺肿瘤术前定位的一种敏感方法。我们旨在确定内镜超声在胰腺胰岛素瘤定位中的性能特征，并评估肿瘤大小与血清C肽水平、最低血糖水平和胰岛素水平之间的关系。
纳入根据临床和实验室检查结果怀疑患有胰岛素瘤的患者。进行内镜超声检查，若发现肿瘤，则将患者转诊进行手术。
共有52例患者（男24例，女28例）接受了内镜超声检查，平均年龄42.4岁，其中43例患者接受了手术。1例患者经腹部超声和腹部CT扫描均发现肿瘤。内镜超声检测胰岛素瘤的总体敏感性和准确性分别为89.5%和83.7%。内镜超声检测胰头、胰体和胰尾病变的敏感性分别为92.6%、78.9%和40.0%。手术中，C肽、最低血糖、胰岛素血水平与肿瘤大小之间无相关性。
内镜超声是检测胰岛素瘤的一种准确方法。其准确性取决于肿瘤的位置，对胰头肿瘤的检测准确性最高。
Zotero 插件