Muscatiello N, Cuomo R, Gentile M, De Francesco V, Stoppino V, Contillo A, Salcuni A, Natale C, Panella C, Ierardi E
Gastroenterology Unit, Ospedali Riuniti of Foggia, Viale L. Pinto, 71100 Foggia, Italy.
Abdom Imaging. 2003 Nov-Dec;28(6):859-61. doi: 10.1007/s00261-003-0039-5.
A 17-year-old female patient with features of epilepsy was treated with valproic acid. Two years later, hypoglycemia and hyperinsulinemia appeared. Transabdominal ultrasonography, spiral computed tomography, and indium-111 Octreoscan were performed without positive results. Endoscopic ultrasonography identified an oval tumor in the pancreatic tail with a color Doppler hypervascular pattern. Surgical enucleation decreased levels of insulin and C-peptide within 20 min, and the patient became free of symptoms and medications.
一名有癫痫症状的17岁女性患者接受了丙戊酸治疗。两年后，出现低血糖和高胰岛素血症。经腹超声、螺旋计算机断层扫描和铟-111奥曲肽扫描均未得到阳性结果。内镜超声检查发现胰尾有一个椭圆形肿瘤，彩色多普勒显示为高血管模式。手术摘除肿瘤后20分钟内胰岛素和C肽水平下降，患者症状消失且无需再服药。
