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Roux-en-Y胃旁路术后难治性胃轻瘫:植入式起搏器的外科治疗

Refractory gastroparesis after Roux-en-Y gastric bypass: surgical treatment with implantable pacemaker.

作者信息

Salameh J R, Schmieg Robert E, Runnels J Matt, Abell Thomas L

机构信息

Department of Surgery, University of Mississippi Medical Center, Jackson, MS, USA.

出版信息

J Gastrointest Surg. 2007 Dec;11(12):1669-72. doi: 10.1007/s11605-007-0331-8. Epub 2007 Sep 29.

Abstract

BACKGROUND

Gastroparesis is a rare complication of Roux-en-Y gastric bypass. We evaluate the role of gastric electrical stimulation in medically refractory gastroparesis.

METHODS

Patients with refractory gastroparesis after gastric bypass for morbid obesity were studied. After behavioral and anatomic problems were ruled out, the diagnosis of disordered gastric emptying was confirmed by radionuclide gastric emptying. Temporary endoscopic stimulation was used first to assess response before implanting a permanent device.

RESULTS

Six patients, all women with mean age of 42 years, were identified. Two patients ultimately had reversal of their surgery with gastro-gastrostomy, while another had a total gastrectomy with persistence of symptoms in all three. Five of the patients evaluated had insertion of a permanent gastric pacemaker, with pacing lead implanted on the gastric pouch (2), the antrum of the reconstructed stomach (1), or the proximal Roux limb (2). Nausea and emesis improved significantly postoperatively; mean total symptom score decreased from 15 to 11 out of 20. There was also a persistent improvement in gastric emptying postoperatively based on radionuclide testing.

CONCLUSION

If medical therapy fails, electrical stimulation is a viable option in selected patients with gastroparesis symptoms complicating gastric bypass and should be considered in lieu of reversal surgery or gastrectomy.

摘要

背景

胃轻瘫是Roux-en-Y胃旁路手术罕见的并发症。我们评估胃电刺激在药物治疗无效的胃轻瘫中的作用。

方法

对病态肥胖患者行胃旁路手术后发生难治性胃轻瘫的患者进行研究。排除行为和解剖学问题后,通过放射性核素胃排空检查确诊胃排空障碍。在植入永久性装置之前,首先使用临时内镜刺激来评估反应。

结果

共纳入6例患者,均为女性,平均年龄42岁。2例患者最终行胃胃吻合术逆转手术,另1例行全胃切除术,3例患者症状均持续存在。5例接受评估的患者植入了永久性胃起搏器,起搏导线分别植入胃囊(2例)、重建胃窦(1例)或近端空肠袢(2例)。术后恶心和呕吐明显改善;平均总症状评分从20分中的15分降至11分。放射性核素检查显示术后胃排空也持续改善。

结论

如果药物治疗失败,电刺激对于胃旁路术后出现胃轻瘫症状的特定患者是一种可行的选择,应考虑以此替代逆转手术或胃切除术。

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