Kung S P, Lui W Y, P'eng F K
Department of Surgery, Veterans General Hospital, Taipei, Taiwan, R.O.C.
Surg Today. 1995;25(10):911-5. doi: 10.1007/BF00311758.
The possible factors contributing to delayed-return gastric emptying (DRGE) after gastrojejunostomy were analyzed through a review of 955 consecutive patients who had undergone gastric surgery for the first time, which revealed 23 patients who had experienced DRGE. Of 7 consecutive patients who had undergone a reoperation for postsurgical gastroparesis syndrome, 3 were found to have experienced persistent DRGE. The chi-squared and/or Student's t-tests showed the significant factors to be (a) an age over 60, and (b) a history or nonresection gastric bypass, Roux-en-Y reconstruction, or reoperation for the preexistence of postoperative gastroparesis, with P values of less than 0.05. There was a higher incidence of DRGE in patients who had received a vagotomy, and there were increasing nutritional indices when patients were recovered from DRGE; however, vagotomy and malnutrition could not be considered independent variables. In conclusion, the incidence of DRGE was significant in patients aged over 60 who had undergone gastrojejunostomy, with nongastric resection, Roux-en-Y reconstruction, or reoperation for gastroparesis. In the event of DRGE, a longer period of supportive treatment is required to avoid unnecessary second surgery as most patients recover spontaneously, whereas a high incidence of persistent DRGE may occur following early reoperation.
通过回顾955例首次接受胃部手术的连续患者,分析了胃空肠吻合术后导致胃排空延迟(DRGE)的可能因素,其中发现23例患者出现了DRGE。在7例因术后胃轻瘫综合征接受再次手术的连续患者中,有3例出现了持续性DRGE。卡方检验和/或学生t检验显示,显著因素为:(a)年龄超过60岁,(b)有非切除性胃旁路术、Roux-en-Y重建术病史或因术前存在术后胃轻瘫而进行再次手术,P值均小于0.05。接受迷走神经切断术的患者DRGE发生率较高,且患者从DRGE恢复时营养指标有所改善;然而,迷走神经切断术和营养不良不能被视为独立变量。总之,在接受胃空肠吻合术、非胃切除术、Roux-en-Y重建术或因胃轻瘫进行再次手术的60岁以上患者中,DRGE的发生率较高。发生DRGE时,由于大多数患者可自发恢复,因此需要较长时间的支持治疗以避免不必要的二次手术,而早期再次手术后可能会出现较高的持续性DRGE发生率。