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[Description of the binding of chitosan to DNA at different ionic strengths in terms of the theories of ion condensation and adsorption].

作者信息

Vorob'ev E A, Nechipurenko Iu D, Salianov V I, Evdokimov Iu M

出版信息

Biofizika. 2007 Jul-Aug;52(4):636-42.

Abstract

The binding of chitosan molecules to DNA in solutions of different ionic strength has been studied. The data were analyzed in terms of the model of ion condensation and the thermodynamic theory of the binding of protracted ligands to DNA. Combining these approaches made it possible to estimate the sterical and energetic characteristics of chitosan-DNA binding and establish the dependence of the chitosan-DNA binding constant on the ionic strength of solution.

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