Vorob'ev E A, Nechipurenko Iu D, Salianov V I, Evdokimov Iu M
Biofizika. 2007 Jul-Aug;52(4):636-42.
The binding of chitosan molecules to DNA in solutions of different ionic strength has been studied. The data were analyzed in terms of the model of ion condensation and the thermodynamic theory of the binding of protracted ligands to DNA. Combining these approaches made it possible to estimate the sterical and energetic characteristics of chitosan-DNA binding and establish the dependence of the chitosan-DNA binding constant on the ionic strength of solution.
研究了壳聚糖分子在不同离子强度溶液中与DNA的结合情况。根据离子凝聚模型和持久配体与DNA结合的热力学理论对数据进行了分析。结合这些方法，可以估算壳聚糖与DNA结合的空间和能量特征，并确定壳聚糖 - DNA结合常数对溶液离子强度的依赖性。
