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[脂质特性对动物肝脏和血液中生化过程调节的影响]

[Influence of the characteristics of lipids on the regulation of biochemical processes in animal liver and blood].

作者信息

Kozlov M V, Kushnireva E V, Urnysheva V V, Taran Iu P, Shishkina L N

出版信息

Biofizika. 2007 Jul-Aug;52(4):693-8.

Abstract

It has been established experimentally that the character and the scale of interrelations between various parameters of the phospholipid composition and their group-average values depend significantly on the characteristics of lipids (the antioxidative activity, quantity of peroxides, and antiperoxide activity) of animal liver and blood erythrocytes. It was shown that a single injection of low-toxicity Tween 80 and acetone at low doses modifies the intensity of lipid peroxidation in the liver and changes the physicochemical properties of lipids, and the interrelations between the parameters that are coordinated in norm, thereby causing the disturbance of biochemical functions of the liver.

摘要

实验已证实,磷脂组成的各种参数之间相互关系的性质和规模及其组均值,在很大程度上取决于动物肝脏和血液红细胞的脂质特性(抗氧化活性、过氧化物数量和抗过氧化物活性)。结果表明,单次注射低剂量的低毒性吐温80和丙酮会改变肝脏中脂质过氧化的强度,改变脂质的物理化学性质,以及正常情况下相互协调的参数之间的相互关系,从而导致肝脏生化功能紊乱。

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