与在髋部骨折手术和择期髋关节置换术中使用相比，调整剂量肝素用于膝关节置换术中预防血栓栓塞的结果。
Results of adjusted-dose heparin for thromboembolism prophylaxis in knee replacement compared to those found for its use in hip fracture surgery and elective hip replacement.
作者信息
Yen David, Weiss William
机构信息
Department of Surgery, Queen's University, Kingston, Ontario, Canada.
出版信息
Iowa Orthop J. 2007;27:47-51.
The purpose of this study was to compare the results of adjusted-dose heparin (ADH) in the prevention of thromboembolism in knee replacement with those obtained for its use hip fracture surgery and elective hip replacement. Ultrasound was used to diagnose deep vein thrombosis (DVT) and ventilation/perfusion (V/Q) scan to diagnose pulmonary embolus (PE). Analysis of 438 operations was available. DVT was present after 9.7% of knee replacements, 7.2% of hip fracture operations and 6.8% of elective hip replacements. PE occurred in 1.2% of knee replacements, 0.9% of hip fracture operations and 2.5% of elective hip replacements. Proximal DVT occurred in 4.2% of knee replacements, 3.6% of hip fracture operations and 4.3% of elective hip replacements. Complications of heparin occurred in 4.6% of patients. Our ADH protocol was equally effective in prophylaxis against thromboembolism in knee replacement, hip fracture surgery and elective hip replacement. Direct comparison with other methods should not be done because ultrasound was used to screen for DVT.
本研究的目的是比较调整剂量肝素（ADH）在膝关节置换术中预防血栓栓塞的效果与在髋部骨折手术和择期髋关节置换术中的使用效果。采用超声诊断深静脉血栓形成（DVT），通气/灌注（V/Q）扫描诊断肺栓塞（PE）。对438例手术进行了分析。膝关节置换术后DVT发生率为9.7%，髋部骨折手术为7.2%，择期髋关节置换为6.8%。膝关节置换术后PE发生率为1.2%，髋部骨折手术为0.9%，择期髋关节置换为2.5%。近端DVT在膝关节置换术中发生率为4.2%，髋部骨折手术为3.6%，择期髋关节置换为4.3%。4.6%的患者出现肝素并发症。我们的ADH方案在膝关节置换术、髋部骨折手术和择期髋关节置换术中预防血栓栓塞同样有效。由于使用超声筛查DVT，因此不应与其他方法进行直接比较。
Zotero 插件