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[铊中毒诱发儿童系统性红斑狼疮]

[Thallium poisoning which stimulated systemic lupus erythematosus in a child].

作者信息

Montoya-Cabrera M A, Sauceda-García J M, Escalante-Galindo P, López-Morales E

机构信息

Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social.

出版信息

Gac Med Mex. 1991 Jul-Aug;127(4):333-6.

PMID:1790839
Abstract

We report the case of a preschool boy who, without knowledge of his relatives, ingested thallium sulfate in a dose calculated in 30 mg/kg. He presented a systemic lupus erythematosus-like syndrome and only further alopecia oriented the diagnosis of thallium toxicosis; thallium blood levels were; 37.2 micrograms/dl and in urine: 2330 micrograms/L. Treatment with the chelating agent D. penicillamine was effective, the clinical picture disappeared and the decrease of the thallium levels was observed. Thallium intoxication should be considered in the differential diagnosis of connective tissue disease as the above mentioned.

摘要

我们报告了一名学龄前男孩的病例,他在亲属不知情的情况下摄入了按30毫克/千克计算剂量的硫酸铊。他出现了类似系统性红斑狼疮的综合征,仅进一步出现的脱发指向铊中毒的诊断;血液铊水平为37.2微克/分升,尿液中为2330微克/升。使用螯合剂青霉胺治疗有效,临床症状消失,铊水平下降。在上述结缔组织疾病的鉴别诊断中应考虑铊中毒。

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