Treshchinskiĭ A I, Shplapak I P, Chepkiĭ L P, Dmitrieva M B, Kharchenko L A
Vrach Delo. 1989 Mar(3):100-3.
The authors report results of treatment of 16 patients whose disease was caused by premeditated poisoning with thallium fluoride. The first signs of the disease appeared in 5 patients 30-38 hours and in the remaining 2-4 days after ingestion of poisoned food and were manifested by dyspepsia, leg pain. Then neurological symptoms of polyneuritis and encephalomyelitis prevailed. Within 1-3 weeks alopecia, xeroderma, herpetic phenomena appeared. Most patients showed disorders of the psycho-emotional sphere (intoxication encephalopathies of anxiety-paranoia type). Severe grades of thallitoxicosis were marked by involvement of the myocardium, liver and kidneys. Excretion of the nucleus is slow: with the urine (45%), with feces (55%). For correct diagnosis and for solution medical forensic problems examination of the content of thallium in the blood, urine, feces and hair is of importance. Treatment tactics are described in detail.
作者报告了16例因蓄意服用氟化铊中毒致病患者的治疗结果。疾病的首发症状在5例患者中于摄入有毒食物后30 - 38小时出现，其余患者在2 - 4天后出现，表现为消化不良、腿部疼痛。随后，多发性神经炎和脑脊髓炎的神经症状占主导。1 - 3周内出现脱发、皮肤干燥、疱疹现象。大多数患者出现心理 - 情感领域的障碍（焦虑 - 偏执型中毒性脑病）。重度铊中毒的特征是心肌、肝脏和肾脏受累。铊的排泄缓慢：通过尿液排泄（45%），通过粪便排泄（55%）。为了正确诊断和解决法医医学问题，检测血液、尿液、粪便和头发中的铊含量很重要。详细描述了治疗策略。
