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前列腺腺癌伴下颌骨转移瘤:病例报告

Prostatic adenocarcinoma with mandibular metastatic lesion: case report.

作者信息

Reyes Court Daniel, Encina Susana, Levy Irene

机构信息

Departamento de Cirugía y Traumatología Bucal y Máxilofacial, Facultad de Odontología, Universidad de Chile, Independencia, Santiago de Chile.

出版信息

Med Oral Patol Oral Cir Bucal. 2007 Oct 1;12(6):E424-7.

Abstract

Metastatic lesions of primary tumors, which originate in different parts of the body, comprise almost 1 % of different types of oral cancers. These lesions can affect either bones or soft tissues in the maxillofacial region. Whenever the maxillofacial area is affected, the most common location is in the molar region of the mandible. The clinical presentation of mandibular metastasis follows a clinical pattern characterized by irradiated dental pain in the third molar region. The most frequent sign is parethesia of the area innervated by the mandibular alveolar dental nerve. Differential diagnosis and treatment of these patients can be extremely difficult because there a number of pathologic conditions with similar symptoms and because diagnostic examination can be highly confusing. The aim of this article is to present a case of prostatic adenocarcinoma where the only metastasis was found in the jaw. A literature review will be presented, hoping to contribute to the scarce information regarding this lesion, due to its low frequency and atypical expression of this type of metastasis in terms of etiology, biological behavior and treatment.

摘要

原发肿瘤的转移灶起源于身体的不同部位,约占不同类型口腔癌的1%。这些病灶可累及颌面部的骨骼或软组织。当颌面部区域受累时,最常见的部位是下颌磨牙区。下颌转移瘤的临床表现遵循一种临床模式,其特征为第三磨牙区放射性牙痛。最常见的体征是下颌牙槽神经支配区域的感觉异常。这些患者的鉴别诊断和治疗可能极其困难,因为有许多病理状况具有相似症状,且诊断检查可能极具迷惑性。本文旨在介绍一例前列腺腺癌患者,其仅在颌骨发现转移灶。同时将进行文献综述,希望能为关于这种病变的稀缺信息做出贡献,因为其发生率低,且在病因、生物学行为和治疗方面这种转移类型的表现不典型。

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