Irani Soussan
Dental Research Center, Department of Oral Pathology, Dental Faculty, Hamadan University of Medical Sciences, Hamadan, Iran.
J Int Soc Prev Community Dent. 2016 Sep-Oct;6(5):393-401. doi: 10.4103/2231-0762.192935. Epub 2016 Oct 24.
The present review article analyzes the characteristics of metastases to the oral soft tissues from 1937 to 2015. An extensive literature search was performed. All variables such as age, gender, and primary and secondary tumor sites were analyzed. Metastases to the major salivary glands were not included in this review. In general, there were 412 metastatic lesions developed in the oral soft tissues. The male-to-female ratio was approximately 1.8:1. The mean age of the patients at diagnosis was 58. The lung was the most common primary site and the gingiva was the most common metastatic site. The greater part of the histological examination yielded adenocarcinoma. The diagnosis of a metastatic lesion in the oral cavity is a challenge to the clinicians due to the lack of pathognomonic signs and symptoms. Oral metastases usually occur in the advanced stages of cancers, and the interval between appearance and death is usually short. The oral soft tissue metastasis can be easily recognized compared to the metastasis of jawbones. Early detection of oral lesions is important in the case of being the first sign of a malignancy in other parts of body.
本综述文章分析了1937年至2015年间口腔软组织转移瘤的特征。进行了广泛的文献检索。对年龄、性别以及原发和继发肿瘤部位等所有变量进行了分析。本综述未纳入主要唾液腺转移瘤。总体而言，口腔软组织中共出现412个转移病灶。男女比例约为1.8:1。患者诊断时的平均年龄为58岁。肺是最常见的原发部位，牙龈是最常见的转移部位。组织学检查大部分结果为腺癌。由于缺乏特征性的体征和症状，口腔转移瘤的诊断对临床医生来说是一项挑战。口腔转移瘤通常发生在癌症晚期，出现症状至死亡的间隔通常较短。与颌骨转移相比，口腔软组织转移更容易识别。在口腔病变是身体其他部位恶性肿瘤的首发迹象时，早期检测很重要。
