Wallace A Michael, Sattar Naveed
Department of Clinical Biochemistry and Vascular Biochemistry, Glasgow Royal Infirmary, Glasgow, UK.
Clin Biochem Rev. 2007 Aug;28(3):79-92.
In this review we outline clinical features, presentation and pathogenesis of polycystic ovarian syndrome (PCOS), treatment objectives and therapeutic options. We focus on and outline the changing role of the clinical laboratory in diagnosis and treatment of this condition. We also review recent information on the involvement of insulin resistance in the syndrome. We provide some explanation for confusion over the selection of the best hormone measurements for diagnosis. Finally, we outline the best current and future laboratory support for this common condition in young women.
在本综述中,我们概述了多囊卵巢综合征(PCOS)的临床特征、表现及发病机制、治疗目标和治疗选择。我们重点关注并概述了临床实验室在该疾病诊断和治疗中不断变化的作用。我们还回顾了有关胰岛素抵抗在该综合征中作用的最新信息。我们对诊断时最佳激素检测项目选择方面的困惑做出了一些解释。最后,我们概述了目前针对年轻女性这一常见疾病所能提供的最佳实验室支持以及未来的相关支持。