Bocková M, Chládek J, Jurák P, Halámek J, Rektor I
First Department of Neurology, Masaryk University, St Anne's Hospital, 656 91, Brno, Czech Republic.
Clin Neurophysiol. 2007 Dec;118(12):2625-36. doi: 10.1016/j.clinph.2007.07.025. Epub 2007 Oct 2.
The study was designed to investigate the neurocognitive network in the frontal and lateral temporal cortices that is activated by the complex cognitive visuomotor tasks of letter writing.
Eight epilepsy surgery candidates with implanted intracerebral depth electrodes performed two tasks involving the writing of single letters. The first task consisted of copying letters. In the second task, the patients were requested to write any other letter. The cognitive load of the second task was increased mainly by larger involvement of the executive functions. The task-related ERD/ERS of the alpha, beta and gamma rhythms was studied.
The alpha and beta ERD as the activational correlate of writing of single letters was found in the sensorimotor cortex, anterior cingulate, premotor, parietal cortices, SMA and the temporal pole. The alpha and beta ERD linked to the increased cognitive load was present moreover in the dorsolateral and ventrolateral prefrontal cortex, orbitofrontal cortex and surprisingly also the temporal neocortex. Gamma ERS was detected mostly in the left motor cortex.
Particularly the temporal neocortex was activated by the increased cognitive load.
The lateral temporal cortex together with frontal areas forms a cognitive network processing executive functions.
本研究旨在探究额叶和颞叶外侧皮质中的神经认知网络，该网络由书写字母这一复杂的认知视觉运动任务所激活。
八名植入脑内深度电极的癫痫手术候选者执行了两项涉及书写单个字母的任务。第一项任务是抄写字母。在第二项任务中，要求患者书写任意其他字母。第二项任务的认知负荷主要因执行功能的更大参与而增加。研究了与任务相关的α、β和γ节律的事件相关去同步化/事件相关同步化。
在感觉运动皮层、前扣带回、运动前区、顶叶皮层、辅助运动区和颞极发现了作为书写单个字母激活相关物的α和β事件相关去同步化。与认知负荷增加相关的α和β事件相关去同步化还存在于背外侧和腹外侧前额叶皮层、眶额皮层，令人惊讶的是还存在于颞叶新皮层。γ事件相关同步化主要在左侧运动皮层检测到。
特别是颞叶新皮层因认知负荷增加而被激活。
颞叶外侧皮质与额叶区域共同形成一个处理执行功能的认知网络。
