Heath D, Yacoub M
Department of Pathology, Royal Liverpool University Hospital.
J Clin Pathol. 1991 Dec;44(12):1003-6. doi: 10.1136/jcp.44.12.1003.
The numbers of mast cells/mm2 of lung parenchyma were counted in four controls, 15 cases of primary plexogenic pulmonary arteriopathy (PPA), and 17 cases in which the arteriopathy was secondary to congenital heart disease, to determine if increased numbers occur in PPA and with what stage of disease they might be associated. Considerable accumulations of lung mast cells may occur in this disease, but these are not closely related to any particular histological stage in the development of the arteriopathy. It is postulated that while mast cells could conceivably exert a vasodilatory effect on constricted small pulmonary arteries, it seems more likely that they are part of the parenchymal changes that commonly develop in this disease.
对4名对照者、15例原发性丛状肺动脉病（PPA）患者以及17例继发于先天性心脏病的肺动脉病患者的肺实质中肥大细胞数量进行/mm²计数，以确定PPA中肥大细胞数量是否增加以及它们可能与疾病的哪个阶段相关。在这种疾病中可能会出现大量肺肥大细胞积聚，但这些与动脉病发展的任何特定组织学阶段并无密切关联。据推测，虽然肥大细胞可以想象地对收缩的小肺动脉发挥血管舒张作用，但它们似乎更有可能是这种疾病中常见的实质变化的一部分。
