Yousefzadi Morteza, Sonboli Ali, Karimic Farah, Ebrahimi Samad Nejad, Asghari Behvar, Zeinalia Amineh
Department of Ecology and Systematic, Research Institute of Applied Science, ACECR, Evin, P.O. Box 19835-169, Tehran, Iran.
Z Naturforsch C J Biosci. 2007 Jul-Aug;62(7-8):514-8. doi: 10.1515/znc-2007-7-809.
The aerial parts of Salvia multicaulis, S. sclarea and S. verticillata were collected at full flowering stage. The essential oils were isolated by hydrodistillation and analyzed by combination of capillary GC and GC-MS. The in vitro antimicrobial activity of the essential oils were studied against eight Gram-positive and Gram-negative bacteria (Bacillus subtilis, Bacillus pumulis, Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) and three fungi (Candida albicans, Saccharomyces cerevisiae and Aspergillus niger). The results of antibacterial activity tests of the essential oils according to the disc diffusion method and MIC values indicated that all the samples have moderate to high inhibitory activity against the tested bacteria except for P. aeruginosa which was totally resistant. In contrast to antibacterial activity, the oils exhibited no or slight antifungal property, in which only the oil of S. multicaulis showed weak activity against two tested yeasts, C. albicans and S. cerevisiae.
在盛花期采集了多花鼠尾草、南欧丹参和轮伞鼠尾草的地上部分。通过水蒸馏法分离出挥发油，并结合毛细管气相色谱和气相色谱 - 质谱联用仪进行分析。研究了这些挥发油对8种革兰氏阳性和革兰氏阴性细菌（枯草芽孢杆菌、短小芽孢杆菌、粪肠球菌、金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌、铜绿假单胞菌和肺炎克雷伯菌）以及3种真菌（白色念珠菌、酿酒酵母和黑曲霉）的体外抗菌活性。根据纸片扩散法和最低抑菌浓度值进行的挥发油抗菌活性测试结果表明，除完全耐药的铜绿假单胞菌外，所有样品对受试细菌均具有中度至高抑制活性。与抗菌活性相反，这些挥发油没有或仅有轻微的抗真菌特性，其中只有多花鼠尾草的挥发油对两种受试酵母白色念珠菌和酿酒酵母表现出微弱活性。
