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白花丹参精油及其主要成分的抗菌活性

Antimicrobial activity of essential oil and major constituents of Salvia chloroleuca.

作者信息

Yousefzadi Morteza, Sonboli Ali, Ebrahimi Samad Nejad, Hashemi Seid Hasan

机构信息

Department of Marine Biology, Faculty of Sciences, Hormozgan University, Bandar Abbas, Iran.

出版信息

Z Naturforsch C J Biosci. 2008 May-Jun;63(5-6):337-40. doi: 10.1515/znc-2008-5-605.

DOI:10.1515/znc-2008-5-605
PMID:18669017
Abstract

The aerial parts of Salvia chloroleuca were collected at full flowering stage at Shahrestanak (Tehran province of Iran). The essential oil was isolated by hydrodistillation and analyzed by combination of capillary GC and GC-MS. Thirty-four components were identified, representing 98.5% of the total oil. beta-Pinene (10.6%), alpha-pinene (9.0%), beta-caryophyllene (9.0%), 1,8-cineole (9.0%) and carvacrol (7.9%) were the main components. The in vitro antimicrobial activity of the essential oil of S. chloroleuca was studied against seven Gram-positive and Gram-negative bacteria (Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, S. epidermidis, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) and three fungi (Candida albicans, Saccharomyces cerevisiae and Aspergillus niger); the disc diffusion method and MIC values indicated that the oil exhibited moderate to high antimicrobial activity.

摘要

在伊朗德黑兰省的沙雷斯坦纳克,于鼠尾草绿花鼠尾草盛花期采集其地上部分。通过水蒸馏法分离出挥发油,并采用毛细管气相色谱和气相色谱 - 质谱联用技术进行分析。共鉴定出34种成分,占总油含量的98.5%。β-蒎烯(10.6%)、α-蒎烯(9.0%)、β-石竹烯(9.0%)、1,8-桉叶素(9.0%)和香芹酚(7.9%)为主要成分。对绿花鼠尾草挥发油针对7种革兰氏阳性菌和革兰氏阴性菌(枯草芽孢杆菌、粪肠球菌、金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌、铜绿假单胞菌和肺炎克雷伯菌)以及3种真菌(白色念珠菌、酿酒酵母和黑曲霉)的体外抗菌活性进行了研究;纸片扩散法和最低抑菌浓度值表明该油具有中度至高抗菌活性。

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